Epigenetic regulation of bone mass

EM Curtis, NR Fuggle, C Cooper, NC Harvey - Best Practice & Research …, 2022 - Elsevier
… -omics technologies have further revealed susceptibility loci, … increase in bone formation
and reduction in bone loss, raising … that differential methylation signatures in bone tissue which …

Epigenetics and bone remodeling

A Husain, MA Jeffries - Current osteoporosis reports, 2017 - Springer
… with RNA-seq profiling to determine gene transcription effects [… differentially methylated loci
from subchondral bone regions … Further research in this area will no doubt reveal additional …

[HTML][HTML] Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis

HK Datta, MK Kringen, SP Tuck, G Salpingidou… - International Journal of …, 2022 - mdpi.com
… Our study shows that expression of the neurological transcriptional factor zinc finger of the
… between the transcription factor and osteoporosis and BMD in transiliac bone biopsies from …

[HTML][HTML] Genetics and epigenetics of bone remodeling and metabolic bone diseases

L Oton-Gonzalez, C Mazziotta, MR Iaquinta… - International Journal of …, 2022 - mdpi.com
bone formation and osteoclastic bone resorption may lead to the onset of bone metabolic
diseases, including osteoporosis [43], … data revealed the involvement of circRNAs in bone

The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo [a] pyrene exposed F1 and F3 male medaka

T Wan, J Mo, DWT Au, X Qin, NYK Tam, RYC Kong… - Epigenetics, 2023 - Taylor & Francis
revealed that osteoblast numbers at the vertebral bone … of differential methylation and gene
expression profiles related … may protect from pathological bone loss [Citation115]. NDUFS2 is …

A Genomewide Association Study Identifies Two Sex‐Specific Loci, at SPTB and IZUMO3, Influencing Pediatric Bone Mineral Density at Multiple Skeletal Sites

A Chesi, JA Mitchell, HJ Kalkwarf… - Journal of bone and …, 2017 - academic.oup.com
… In doing so, we identified five loci that achieved genome widebone acquisition may differ
from those that impact bone loss … , which did not reveal any genomewide significant loci for …

Differential DNA methylation and mRNA transcription in gingival tissues in periodontal health and disease

H Kim, F Momen‐Heravi, S Chen… - Journal of clinical …, 2021 - Wiley Online Library
differentially methylated CpG sites and regions, differentially expressed genes (DEGs), and
genes with concomitant differential methylation at … revealed no differentially methylated CpG …

Identification of circRNA Expression Profiles in BMSCs from Glucocorticoid‐Induced Osteoporosis Model

Z Chen, W Lin, S Zhao, X Mo, Z Wen… - Stem Cells …, 2022 - Wiley Online Library
… To characterize GC-induced bone loss in a small animal model, … most commonly used model
for osteoporosis, based on micro-… [48] revealed that miR-365a-3p negatively regulates the …

Epigenetics, bone remodeling and osteoporosis

S Yang, X Duan - Current stem cell research & therapy, 2018 - ingentaconnect.com
… . compared the genome wide methylation profile between 27 osteoporosis patients and 26
Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and …

[HTML][HTML] Identification of aberrantly-expressed long non-coding RNAs in osteoblastic cells from osteoporotic patients

F Centofanti, M Santoro, M Marini, VV Visconti… - Biomedicines, 2020 - mdpi.com
… In this study, we analysed the expression profile of 84 lncRNAs … roles in bone homeostasis
and osteoporosis pathways and the … The Volcano plot shows the significant lncRNAs that we …