Identification of aberrantly-expressed long non-coding RNAs in osteoblastic cells from osteoporotic patients
F Centofanti, M Santoro, M Marini, VV Visconti… - Biomedicines, 2020 - mdpi.com
… In this study, we analysed the expression profile of 84 lncRNAs … roles in bone homeostasis
and osteoporosis pathways and the … The Volcano plot shows the significant lncRNAs that we …
and osteoporosis pathways and the … The Volcano plot shows the significant lncRNAs that we …
The integrative analysis of DNA methylation and mRNA expression profiles confirmed the role of selenocompound metabolism pathway in Kashin-Beck disease
… ), and other skeletal disorders were excluded from this study. … Differentially methylated CpG
sites were identified using the … ECM formation and is related to osteoporosis in KBD patients […
sites were identified using the … ECM formation and is related to osteoporosis in KBD patients […
The epigenome at the crossroad between social factors, inflammation, and osteoporosis risk
JA Riancho, SL Brennan-Olsen - Clinical Reviews in Bone and Mineral …, 2017 - Springer
… Epidemiological studies have revealed an influence of a variety … showed several differentially
methylated regions, which … with specific DNA methylation profiles in adult peripheral blood …
methylated regions, which … with specific DNA methylation profiles in adult peripheral blood …
A Genomewide Association Study Identifies Two Sex‐Specific Loci, at SPTB and IZUMO3, Influencing Pediatric Bone Mineral Density at Multiple Skeletal Sites
A Chesi, JA Mitchell, HJ Kalkwarf… - Journal of bone and …, 2017 - academic.oup.com
… In doing so, we identified five loci that achieved genome wide … bone acquisition may differ
from those that impact bone loss … , which did not reveal any genomewide significant loci for …
from those that impact bone loss … , which did not reveal any genomewide significant loci for …
Differential DNA methylation and mRNA transcription in gingival tissues in periodontal health and disease
… differentially methylated CpG sites and regions, differentially expressed genes (DEGs), and
genes with concomitant differential methylation at … revealed no differentially methylated CpG …
genes with concomitant differential methylation at … revealed no differentially methylated CpG …
[PDF][PDF] The association between knee synovial methylation and knee osteoarthritis in different ethnic populations from different altitude
Z Li, D Zhang, R Ren, Z Lu, G Li, T Geng, J Luosong… - 2024 - assets-eu.researchsquare.com
… differential genes corresponding to differential methylation … The present study shows
that OA is a common degenerative … of separating OA studies from skeletal sites and help us …
that OA is a common degenerative … of separating OA studies from skeletal sites and help us …
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease
A Garcia-Gomez, T Li, C de la Calle-Fabregat… - Nature …, 2021 - nature.com
… We first obtained genome-wide DNA methylation profiles of BM-… Furthermore, we validated
differentially methylated genes … of distal femurs revealed a marked bone loss evidenced by a …
differentially methylated genes … of distal femurs revealed a marked bone loss evidenced by a …
Bone Trans-omics: Integrating Omics to Unveil Mechanistic Molecular Networks Regulating Bone Biology and Disease
… ) to reveal new molecular mechanisms that regulate bone biology and … , they identified 30
differentially methylated sites potentially … Single-cell sequencing data sets that profile bone cell …
differentially methylated sites potentially … Single-cell sequencing data sets that profile bone cell …
Genome-wide differential methylation profiles from two terpene-rich medicinal plant extracts administered in osteoarthritis rats
… ], improve bone growth [10], and manage bone-related diseases, such as OA and osteoporosis
[… 3B), which shows that 929 genes contained CpGs from all three regions. With respect to …
[… 3B), which shows that 929 genes contained CpGs from all three regions. With respect to …
Epigenetic mechanisms in bone development
… of differentially methylated regions of interest (DMROI) across a … A genomewide methylation
study of severe vitamin D deficiency in … Genome-wide profiling of bone reveals differentially …
study of severe vitamin D deficiency in … Genome-wide profiling of bone reveals differentially …