Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease
…, L Jostins, CA Anderson, Uk Ibd Genetics Consortium… - Nature …, 2017 - nature.com
… using an expression atlas of primary human cells 30 . Strong enrichment was observed in
… 170 Crohn's disease susceptibility loci were identified from a recent large meta-analysis 31 (…
… 170 Crohn's disease susceptibility loci were identified from a recent large meta-analysis 31 (…
Genome-wide association study identifies African-specific susceptibility loci in African Americans with inflammatory bowel disease
… IBD loci and associations.8, 9, 10, 11 We hypothesized that high-density genome-wide
association study (GWAS) of IBD in … IBD has demonstrated unique, African-specific loci, as well as …
association study (GWAS) of IBD in … IBD has demonstrated unique, African-specific loci, as well as …
Identification of three novel susceptibility loci for inflammatory bowel disease in Koreans in an extended genome-wide association study
… in the clinical characteristics of IBD among different ethnicities, the … of IBD, we identified
two new susceptibility loci for IBD and … The 95% credible set in each locus was defined as the …
two new susceptibility loci for IBD and … The 95% credible set in each locus was defined as the …
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility
…, SPARC IBD Network, UK IBD Genetics Consortium… - Nature …, 2022 - nature.com
… Genome-wide association studies (GWASs) have identified … GWASs in CD, and inflammatory
bowel disease (IBD) more … Two different exome capture platforms were employed during …
bowel disease (IBD) more … Two different exome capture platforms were employed during …
A Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn's Disease in Japanese Individuals
Y Kakuta, Y Kawai, T Naito, A Hirano… - … of Crohn's and …, 2019 - academic.oup.com
… numerous susceptibility loci for Crohn’s disease [CD]. … Inflammatory bowel disease [IBD] is
characterised by chronic … sample sets, we conducted two separate GWASs, followed by a meta…
characterised by chronic … sample sets, we conducted two separate GWASs, followed by a meta…
A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn's disease
… by inflammatory bowel diseases, especially in CD patients 8 . … different or even opposite
functional effects in both diseases. … IBDGC Crohn’s Disease Genome-Wide Association Study …
functional effects in both diseases. … IBDGC Crohn’s Disease Genome-Wide Association Study …
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
… We identified 25 new susceptibility loci, 3 of which contain … In two cases, we have implicated
genes in which different … traits (Crohn's disease, ulcerative colitis and IBD), defined by the …
genes in which different … traits (Crohn's disease, ulcerative colitis and IBD), defined by the …
Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility
…, SPARC IBD Network, UK IBD Genetics Consortium… - medRxiv, 2021 - medrxiv.org
… Genome-wide association studies (GWAS) have identified hundreds of loci associated
with Crohns disease (CD), however, as with all complex diseases, deriving pathogenic …
with Crohns disease (CD), however, as with all complex diseases, deriving pathogenic …
Multivariate genome-wide association study models to improve prediction of Crohn's disease risk and identification of potential novel variants
D Garza-Hernandez, K Estrada, V Trevino - Computers in biology and …, 2022 - Elsevier
… Crohn's disease (CD) is a type of inflammatory bowel … analysis of a CD dataset different from
the one commonly used, and we … Heritability, defined as the proportion of variance of a trait …
the one commonly used, and we … Heritability, defined as the proportion of variance of a trait …
[HTML][HTML] Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
… identified 163 susceptibility loci for inflammatory bowel disease, mostly … and ulcerative colitis
as currently defined. … on a range of different genome-wide association study (GWAS) chips. …
as currently defined. … on a range of different genome-wide association study (GWAS) chips. …