Shared genetic etiology underlying Alzheimer's disease and major depressive disorder

MW Lutz, D Sprague, J Barrera… - Translational psychiatry, 2020 - nature.com
studies suggested that risk genes for MDD may be involved in LOAD 13,14,15 . Genome-wide
association studies … in each cohort from the Psychiatric Genomics Consortium 39 . The …

GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

A Rongve, A Witoelar, A Ruiz, L Athanasiu… - Scientific reports, 2019 - nature.com
… We performed a genome wide association study in Norwegian and European cohorts of 720
… One additional genetic locus previously linked to psychosis in Alzheimer’s disease, ZFPM1 (…

Effects of vitamin D use on outcomes of psychotic symptoms in Alzheimer disease patients

L Wang, J Ying, P Fan, EA Weamer… - The American Journal of …, 2019 - Elsevier
… and compared these signatures genome-wide, revealing unexpected drug–disease “connections” …
Recently, our genetic association study of AD + P versus AD – P patients found that …

Schizophrenia, bipolar disorder, and Alzheimer's disease are not causal factors of bone mineral density: a Mendelian randomization analysis

Z Cui, X Meng, S Zhuang, Z Liu, F Zhou… - Calcified Tissue …, 2020 - Springer
disorder (BD) is a chronic and recurrent psychiatric disorder … the progress of genome-wide
association studies (GWAS) … We selected SNPs with genome-wide association and …

Genome-wide association study of circadian rhythmicity in 71,500 UK biobank participants and polygenic association with mood instability

A Ferguson, LM Lyall, J Ward, RJ Strawbridge… - …, 2018 - thelancet.com
… of this study To our knowledge, this is the first large scale genome-wide association study of
… We also assess the degree of genetic correlation between low RA and several psychiatric

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk

IE Jansen, JE Savage, K Watanabe, J Bryois… - Nature …, 2019 - nature.com
… Here, we performed a large genome-wide association study … Phase 1 involved a
genome-wide meta-analysis for clinically … (Alzheimer’s disease working group of the Psychiatric

Adolescent verbal memory as a psychosis endophenotype: a genome-wide association study in an ancestrally diverse sample

B Wang, O Giannakopoulou, I Austin-Zimmerman… - Genes, 2022 - mdpi.com
… deficits in psychosis. However, few studies have investigated the genetic basis of verbal
memory in a neurodevelopmental context, and most genome-wide association studies (GWASs) …

[HTML][HTML] Genome-wide association study of dimensional psychopathology using electronic health records

TH McCoy Jr, VM Castro, KL Hart, AM Pellegrini… - Biological …, 2018 - Elsevier
Research Domain Criteria definitions from narrative hospital discharge notes in a large biobank.
We conducted a genome-wide association study … Family studies of psychiatric illnesses …

[HTML][HTML] Genome-wide association studies of brain imaging phenotypes in UK Biobank

LT Elliott, K Sharp, F Alfaro-Almagro, S Shi, KL Miller… - Nature, 2018 - nature.com
… The effects of neurological and psychiatric disorders such as Alzheimer’s disease, … ,
ageing and disease. In this study, we carried out genome-wide association studies (GWASs) for …

Genome wide association neural networks (GWANN) identify novel genes linked to family history of Alzheimer's disease in the UK Biobank

U Ghose, W Sproviero, L Winchester, M Fernandes… - medRxiv, 2022 - medrxiv.org
… , genome wide association studies (GWAS) have revolutionised our understanding of the
inherited basis of disease … DAB1 has previously been associated with psychosis in AD 14 , and …