[HTML][HTML] Epigenetic regulation by long noncoding RNAs in osteo-/adipogenic differentiation of mesenchymal stromal cells and degenerative bone diseases

K Xia, LY Yu, XQ Huang, ZH Zhao… - World Journal of Stem …, 2022 - ncbi.nlm.nih.gov
… of bone homeostasis can trigger degenerative bone diseases, including osteoporosis and
osteoarthritis. … , epigenetic modifications (ie, DNA methylation, histone modifications, and the …

The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo [a] pyrene exposed F1 and F3 male medaka

T Wan, J Mo, DWT Au, X Qin, NYK Tam, RYC Kong… - Epigenetics, 2023 - Taylor & Francis
… level of differential methylation and gene expression profilesosteoporosis in men [Citation97].
CHSY1 is required for … However, genome-wide DNA methylation profiling and their …

[HTML][HTML] Multiple targets identified with genome wide profiling of small RNA and mRNA expression are linked to fracture healing in mice

M Bourgery, E Ekholm, K Fagerlund, A Hiltunen… - Bone Reports, 2021 - Elsevier
… Increasing evidence shows that small noncoding RNAs are … fracture healing, genome
wide expression profiles of tiRNAs, … and, compared to intact bone and articular cartilage at 2 …

DNA methylation and the social gradient of osteoporotic fracture: a conceptual model

SL Brennan-Olsen, RS Page, M Berk, JA Riancho… - Bone, 2016 - Elsevier
… associated with fracture risk via genome-wide association studies (GWAS) … differentially
methylated genes that are related to skeletal development [16]. A role for DNAm in osteoporosis

Shared genetic architecture between rheumatoid arthritis and varying osteoporotic phenotypes

M Kasher, MB Freidin, FMK Williams… - Journal of Bone and …, 2020 - academic.oup.com
skeletal sites reported in UK Biobank as well as OP fracture acquired from the Genetic Factors
for Osteoporosis … specified genomic region, 45 genomic regions were revealed with high …

Inter-individual gene variants associated with trabecular bone plasticity: A step forward in the personal genomics of degenerative bone disease

E Caso, CC Sabiers, D López-Guillén, J Caso… - Injury, 2017 - Elsevier
… future treatment options for early osteoarthritis (OA) of the hip … gene variants observed in
genome-wide association study (… individual exomic profiles associated with OA revealed clear …

Identification of aberrantly-expressed long non-coding RNAs in osteoblastic cells from osteoporotic patients

F Centofanti, M Santoro, M Marini, VV Visconti… - Biomedicines, 2020 - mdpi.com
… Recently, genome-wide association studies (GWASs) have … roles in bone homeostasis and
osteoporosis pathways and … The Volcano plot shows the significant lncRNAs that we found …

A whole-genome transcriptome analysis of articular chondrocytes in secondary osteoarthritis of the hip

T Aki, K Hashimoto, M Ogasawara, E Itoi - PloS one, 2018 - journals.plos.org
… articular cartilage, synovium, and subchondral bone [1]. It is … (96 combinations in total)
revealed 352 upregulated and 159 … is the first study to investigate genome-wide changes in gene …

The first international workshop on the epigenetics of osteoarthritis

IM Meulenbelt, N Bhutani, W den Hollander… - Connective tissue …, 2017 - Taylor & Francis
… and sclerosis of the underlying bone. The disease … genome-wide analysis of the transcriptome
and methylome of articular cartilage revealed that only 24% of the differentially methylated

Discovery of potential biomarkers for osteoporosis diagnosis by individual omics and multi-omics technologies

J Yang, J Wu - Expert Review of Molecular Diagnostics, 2023 - Taylor & Francis
Osteoporosis (OP) is a systemic skeletal disease … rare variants obtained from genome wide
sequencing to complex … The hub differentially expressed genes with differential methylation