… skeletal pathologies and disorders, such as osteoporosis … genome-wide and gene-specific
DNA methylation in primate … were significantly differentially methylated across comparative …

… degradation, subchondral bone remodelling and inflammation … Recent studies revealed that
DNA methylation is one of the … numerous differently methylated CpGs in enhancer regions […

… -targeted genome-wide methylome studies to identify novel genes or regions affected by
the disease. The standardization techniques used in these non-targeted genome-wide assays …

… delays chondrocyte loss and cartilage erosion during osteoarthritis development [34]. While
… with genome-wide analyses revealed that rs11614913T in the MIR196A2 gene in bone …

… differentially methylated regions and 1,317 differentially … late phases of temporomandibular
joint osteoarthritis, and 80% of … condyles of genome-wide methylation patterns were similar in …

… makes the genome-wide analysis of chromatin profiling feasible, … Citation118) and differentially
methylated regions are enriched in … tool to detect skeletal diseases such as osteoporosis. …

… A genome-wide DNA methylation study performed on the … , identified 550 CpGs with differential
methylation, 83 of the CpGs … areas of apparent new tissue formation composed of a bony …

… skeletal diseases such as osteoporosis and osteoarthritis, … It was revealed that Bmncr
upregulates the extracellular … that DNA methylation was altered in a genome-wide manner in …

… of the skeletal system, including osteoarthritis, osteoporosis, … ICRs comprised of differentially
methylated regions (DMRs) … ), and nuclear fractionation studies revealed a large number of …

… in the bone-derived BMSCs of patients with osteoarthritis. Since … bone marrow, the finding
indicates the exhaustion of skeletal … osteoarthritis (OA) and osteoporosis (OP) is important [18]. …