Right versus left ventricular remodeling in heart failure due to chronic volume overload

T Havlenova, P Skaroupkova, M Miklovic… - Scientific Reports, 2021 - nature.com
… The goal of this study was to characterize the functional and … that drive VO chamber remodeling
using pressure–volume analysis, … Genome-wide association study found that variation in …

Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling

T Tobita, S Nomura, T Fujita, H Morita, Y Asano… - Scientific reports, 2018 - nature.com
Genetic basis and genotypes involved in prognosis and left ventricular reverse remodeling
of DCM patients. Genetic analysis was performed on 120 DCM patients. Among them, 78 (…

Genome-wide analysis of left ventricular image-derived phenotypes identifies fourteen loci associated with cardiac morphogenesis and heart failure development

N Aung, JD Vargas, C Yang, CP Cabrera, HR Warren… - Circulation, 2019 - Am Heart Assoc
… The variants in the SH2B3 locus for LVEDV was associated with multiple risk factors that
could mediate the cardiac remodeling process such as blood pressure/hypertension, cholesterol…

Genetic dissection of cardiac remodeling in an isoproterenol-induced heart failure mouse model

JJC Wang, C Rau, R Avetisyan, S Ren… - PLoS …, 2016 - journals.plos.org
… We have previously reported a genetic analysis of β-… cardiac remodeling in the heart, many
of which are less than 1 Mb in size. Then, we utilize expression arrays from left ventricular (LV…

Genetic reduction in left ventricular protein kinase C-α and adverse ventricular remodeling in human subjects

R Hu, MP Morley, J Brandimarto… - Circulation: Genomic …, 2018 - Am Heart Assoc
… Genotypes at rs9912468 strongly associate with PRKCA expression in the left ventricle,
enabling genetic approaches to measure effects of reduced PKC-α in human populations. …

[HTML][HTML] Functional significance of the discordance between transcriptional profile and left ventricular structure/function during reverse remodeling

VK Topkara, KT Chambers, KC Yang, HP Tzeng… - JCI insight, 2016 - ncbi.nlm.nih.gov
… LV remodeled and reverse LV remodeled cardiac phenotypes, we performed a principal
component analysis (… Kyoto Encyclopedia of Genes and Genomes (KEGG) functional analysis

Expression and implication of clusterin in left ventricular remodeling after myocardial infarction

A Turkieh, M Fertin, M Bouvet, P Mulder… - Circulation: Heart …, 2018 - Am Heart Assoc
… To determine if increased plasma CLU levels has a cardiac origin, we analyzed CLU
expression in the LV of rats at 7 days and 2 months post-MI. In this model, cardiac remodeling was …

Genomic analysis of circular RNAs in heart

K Dong, X He, H Su, DJR Fulton, J Zhou - BMC Medical Genomics, 2020 - Springer
… -133, a microRNA that can regulate cardiac remodeling. Interestingly, we detected a novel
… novo analysis of public RNA-seq data sets that were generated from left ventricular tissues …

Decreased left heart flow in fetal lambs causes left heart hypoplasia and pro-fibrotic tissue remodeling

MS Reuter, DJ Sokolowski, J Javier Diaz-Mejia… - Communications …, 2023 - nature.com
left heart hypoplasia secondary to low left heart flow does not undermine the importance of a
genetic predispositions to HLHS and structural left heart … that translate genetic variation to a …

P6330 Genetic predictors of left ventricular reverse remodeling in recent-onset dilated cardiomyopathy assessed by whole exome sequencing

M Kubanek, J Binova, M Kotrc, L Piherova… - European Heart …, 2018 - academic.oup.com
left ventricular reverse remodeling (LVRR) which is a marker of favorable prognosis. We
aimed to assess genetic … exome sequencing and correlate results of genetic testing with LVRR. …