… Whether non-malignant hypertension itself is sufficient to cause reduced glomerular
filtration rate (GFR) is unclear. Therefore, we investigated whether elevated blood pressure (BP) …

… whether elevated blood pressure (BP) also accelerates the gradual decline in the glomerular
… This means that our findings most likely reflect an elevated GFR or hyperfiltration at the …

… blood pressure rhythm, which suggested increased large … The renin-angiotensin-aldosterone
and sympathetic nervous … pathways to arterial stiffness and glomerular hyperfiltration in …

… with hypertension was based on renin‐… glomerular hyperfiltration via mineralocorticoid
receptor activation in macula densa cells. Another possible mechanism is that low extracellular …

… Additionally, low extracellular chloride increased basal … juxtaglomerular cells and stimulate
renin secretion. Interestingly, … vasodilation leading to glomerular hyperfiltration in patients with …

… SGLT2 inhibitors reduce glomerular hyperfiltration. This simple … Since low extracellular
adenosine concentrations and a … renin production in the collecting duct is markedly increased …

… is the presence of glomerular hyperfiltration. The association … affect serum creatinine32 and
might also affect blood pressure,… Glomerular hyperfiltration, high renin, and low- extracellular …

… of magnesium supplementation on the blood pressure, and at … , chronic overstimulation of
the renin-angiotensin-aldosterone … Low extracellular magnesium can result in an abnormal …

… glomerular arteriole, glomerular hyperperfusion and hyperfiltration are weakened (Figure
1) (7). … , SGLT-2is play a vital role in reducing the volume load and lowering blood pressure. …

… in regulating blood pressure and fluid volume by maintaining … and inhibition of aldosterone
synthesis and renin secretion. It has … generating increased blood flow in glomerular capillaries …