[HTML][HTML] Astrocytic connexin43 channels as candidate targets in epilepsy treatment
L Walrave, M Vinken, L Leybaert, I Smolders - Biomolecules, 2020 - mdpi.com
… redistribution of K + and glutamate and display a higher … slices developed spontaneous
epileptiform activity and only … -like events in bicuculline-treated neocortical slices [160]. However, …
epileptiform activity and only … -like events in bicuculline-treated neocortical slices [160]. However, …
[HTML][HTML] … electrode array for epileptiform electrical activity recording under glutamate and GABA modulation on the primary somatosensory cortex of rats
… fabricated to detect epileptiform activity under glutamate (Glu) … pad area was stuck to a PI
thin slice (0.3 mm total thickness) … activity between normal and epileptiform states help to detect …
thin slice (0.3 mm total thickness) … activity between normal and epileptiform states help to detect …
Cortical spreading depression: culprits and mechanisms
AA Mathew, R Panonnummal - Experimental brain research, 2022 - Springer
… using chick retina and neocortical slices. Induction of CSD in … releases glutamine and activates
glutamatergic transmission… the rat neocortex that dopamine can acts on the D2 receptors …
glutamatergic transmission… the rat neocortex that dopamine can acts on the D2 receptors …
[HTML][HTML] N-Acetyl-Aspartyl-Glutamate in Brain Health and Disease
C Morland, K Nordengen - International Journal of Molecular Sciences, 2022 - mdpi.com
… In humans, mGluR3 is strongly expressed in the neocortex, caudate … NAAG to cell cultures
or brain slices are due to the contamination of … of epileptic activity [57,58]. The modulation of …
or brain slices are due to the contamination of … of epileptic activity [57,58]. The modulation of …
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
… epileptiform activity and stimulation-elicited hyperexcitability in neocortical slices from the …
posttraumatic downregulation of glutamate transport and enhances glutamate clearance in …
posttraumatic downregulation of glutamate transport and enhances glutamate clearance in …
Glycine transporters and its coupling with NMDA receptors
F Zafra, I Ibáñez, D Bartolomé-Martín, D Piniella… - Glial Amino Acid …, 2017 - Springer
… activity. For instance, NMDARs containing GluN2B are redistributed away from glutamate
synapses through increased lateral diffusion … glycine that might contribute to glycine release. …
synapses through increased lateral diffusion … glycine that might contribute to glycine release. …
Gap junction blockers: an overview of their effects on induced seizures in animal models
J Manjarrez-Marmolejo… - Current …, 2016 - ingentaconnect.com
… both amplitude and frequency of the epileptiform activity induced in brain slices. In vivo, gap
… concentrations of glutamate and as a consequence the propagation of epileptiform activity […
… concentrations of glutamate and as a consequence the propagation of epileptiform activity […
[HTML][HTML] The paroxysmal depolarization shift: reconsidering its role in epilepsy, epileptogenesis and beyond
H Kubista, S Boehm, M Hotka - International journal of molecular sciences, 2019 - mdpi.com
… in brain slices upon application of the GABA A receptor … of different epileptiform discharges,
including epileptic bursts… interictal discharges using the glutamate receptor antagonist …
including epileptic bursts… interictal discharges using the glutamate receptor antagonist …
[HTML][HTML] Glial glutamate transporter-mediated plasticity: system xc-/xCT/SLC7A11 and EAAT1/2 in brain diseases
… release glutamate via system x c - , which evokes epileptic activity in … In human epileptic foci
in the neocortex, EAAT2 protein … In hippocampal rat brain slices, convulsive agents such as …
in the neocortex, EAAT2 protein … In hippocampal rat brain slices, convulsive agents such as …
[HTML][HTML] Role of NMDA receptor-mediated glutamatergic signaling in chronic and acute neuropathologies
FJ Carvajal, HA Mattison, W Cerpa - Neural plasticity, 2016 - hindawi.com
… triggers biochemical cascades that lead to synaptic damage and … In hippocampal slices in
which ischaemia was induced … is significantly reduced in dopamine-denervated rats leading to …
which ischaemia was induced … is significantly reduced in dopamine-denervated rats leading to …