Three-Dimensional In Vitro Oral Mucosa Models of Fungal and Bacterial Infections

F Tabatabaei, K Moharamzadeh… - Tissue Engineering Part B …, 2020 - liebertpub.com
… In periodontal diseases, invasion of oral epithelial cells by … In candidiasis, invasion of oral
epithelium by Candida … biofilm formation Immortalized human oral keratinocyte cell line (OKF6/…

Therapeutic effect of iturin A on Candida albicans oral infection and its pathogenic factors

D Han, Y Ji, S Yang, P Song, Y Shi… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
… The inhibitory effects of iturin A on the adhesion capacity of C. albicans were evaluated using
human oral cancer cells (KB cells) … Candidalysin contributes to epithelial cell invasion and …

Induction of cyclooxygenase-2 gene by Candida albicans through EGFR, ERK, and p38 pathways in human urinary epithelium

SH Wang, SC Wang, PC Chen, ST Wang… - Medical …, 2017 - academic.oup.com
inhibitors including Toll-like receptor (TLR)-Myd88 inhibitor … In one study of oropharyngeal
candidiasis, the authors … albicans hyphae in human oral epithelial cells. In that report, two …

The potential management of oral candidiasis using anti-biofilm therapies

W Chanda, TP Joseph, W Wang, AA Padhiar… - Medical …, 2017 - Elsevier
… azole agents may produce enormous cell growth inhibition thereby repressing C. albicans
… from severe candidiasis [35]. Another study using an engineered human oral mucosa model …

[HTML][HTML] Candida albicans Sap6 initiates oral mucosal inflammation via the protease activated receptor PAR2

R Kumar, IG Rojas, M Edgerton - Frontiers in Immunology, 2022 - frontiersin.org
cells to induce proinflammatory cytokines, although its ability to interact and activate human
oral epithelial cells … and this signaling was significantly inhibited by PAR2 antagonist peptide …

[HTML][HTML] Is Candida albicans an opportunistic oncogenic pathogen?

AS Sultan, VI Theofilou, A Alfaifi… - PLoS …, 2022 - journals.plos.org
… Acetaldehyde is the first metabolite of ethanol catabolism in epithelial cells and C. albicans.
… linked with inhibition of the apoptotic machinery ultimately leading to tumor development. (2) …

[HTML][HTML] The Anti-Biofilm Efficacy of Caffeic Acid Phenethyl Ester (CAPE) In Vitro and a Murine Model of Oral Candidiasis

PP de Barros, RD Rossoni, MT Garcia… - Frontiers in Cellular …, 2021 - frontiersin.org
… Importantly, this analysis showed that treatment with CAPE inhibited the hyphae formation
that … Epithelial cells of mice release small anti-microbial peptides (AMPs), especially in saliva, …

[HTML][HTML] In vitro and in vivo effects of suloctidil on growth and biofilm formation of the opportunistic fungus Candida albicans

B Zeng, J Li, Y Wang, P Chen, X Wang, J Cui, L Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… albicans; therefore, we performed hyphal growth tests and observed that suloctidil inhibited
epithelial cells via the Hwp1 protein [6]. ECE1 is a hypha-induced gene that is related to cell

[HTML][HTML] Recombinant Human IFNα-2b Response Promotes Vaginal Epithelial Cells Defense against Candida albicans

T Li, X Niu, X Zhang, S Wang, Z Liu - Frontiers in Microbiology, 2017 - frontiersin.org
… affect VEC growth (Figure 1). As shown in Figure 1, after 24 h treatment, high doses (>1.25
mg/mL) of rhIFNα-2b did have a significant inhibitory effect on VEC viability and growth, while …

Adherence of probiotic bacteria to human colon epithelial cells and inhibitory effect against enteric pathogens – In vitro study

N Adriana, M Ilona, Ś Katarzyna… - … journal of dairy …, 2016 - Wiley Online Library
… When adhered to epithelial cells, Candida produces large quantities of extracellular
polymeric substance in solutions enriched with glucose. Slime is considered as a virulent factor …