Haemoglobins of Mycobacterium Tuberculosis and Their Involvement in Management of Environmental Stress

KL Dikshit - Stress and Environmental Regulation of Gene …, 2016 - Wiley Online Library
… HbO of Mtb, scavenges H2O2 and relieves oxidative stress when … Although the role of the
HbN in NO scavenging and the … new truncated hemoglobin from Mycobacterium tuberculosis. …

Truncated Hemoglobin O Carries an Autokinase Activity and Facilitates Adaptation of Mycobacterium tuberculosis Under Hypoxia

MD Hade, D Sethi, H Datta, S Singh… - Antioxidants & redox …, 2020 - liebertpub.com
… bovis bacillus Calmette-Guerin (BCG) carries a potent nitric oxide (NO) scavenging activity
(… Mycobacterium leprae. The complexity in understanding the cellular function(s) of truncated

… between Photochemically Generated Nitric Oxide and Mycobacterium tuberculosis Truncated Hemoglobin N Wild Type and Variant Forms: An Assessment of …

KJ Koebke, MT Waletzko, AA Pacheco - Biochemistry, 2016 - ACS Publications
… –8 M) added to prevent the accumulation of hydrogen peroxide from reduction of oxygen
in the solution. The reduced solution was then either brought into air to make the oxygen-bound …

M. leprae HSP18 suppresses copper (II) mediated ROS generation: effect of redox stress on its structure and function

SK Nandi, A Chakraborty, AK Panda… - International journal of …, 2020 - Elsevier
… Ascenzi et al. demonstrated that M. leprae truncated hemoglobin is involved in scavenging
hydrogen peroxide and thereby helps the pathogen to survive and proliferate in host cells [27]…

New Insights Into the Function of Flavohemoglobin in Mycobacterium tuberculosis: Role as a NADPH-Dependent Disulfide Reductase and D-Lactate-Dependent …

N Thakur, AN Sharma, MD Hade, A Chhaya… - Frontiers in Cellular …, 2022 - frontiersin.org
… to ferric ions by lipid peroxide with the subsequent binding of … peroxide in the cell was
monitored by measuring the absorbance at 560 nm using the standard curve prepared from H 2 O

Heme oxygenase-1 as a pharmacological target for host-directed therapy to limit tuberculosis associated immunopathology

KC Chinta, HT Pacl, A Agarwal, AJC Steyn - Antioxidants, 2021 - mdpi.com
… and patients infected with Mycobacterium tuberculosis (Mtb), … (Hx), a molecular scavenger
of heme, is known to rescue … as superoxide, hydrogen peroxide, hypochlorite, nitric oxide (NO), …

[HTML][HTML] Flavohaemoglobin: The pre-eminent nitric oxide–detoxifying machine of microorganisms

RK Poole - F1000Research, 2020 - ncbi.nlm.nih.gov
NO to NO 3 − via an NO dioxygenase activity. These include the truncated globin of
Mycobacterium tuberculosis… Evidence for a novel inducible anaerobic nitric oxide-scavenging

Oxidative stress and tuberculosis–human immunodeficiency virus coinfection

R Gravier-Hernández, L Gil-del Valle - HIV/AIDS, 2018 - Elsevier
… ) coinfection with Mycobacterium tuberculosis represents a … as superoxide anion (O 2 –
), hydrogen peroxide (H 2 O 2 ), … capacity such as mycothiol and truncated hemoglobins (trHbs) …

Investigating a novel protein-based cofactor: toward elucidating the catalase mechanism of Mycobacterium tuberculosis KatG

T Aziz - 2022 - etd.auburn.edu
… preparations of KatG upon reaction with H2O2 under sustained turnover conditions ……………
on enzyme absorption features during consumption of H2O2 under multiple-turnover/steady…

Proteomics of physiologically relevant stresses on model mycobacterium tuberculosis organisms, and the effects on virulence

M Ganief - 2023 - open.uct.ac.za
… to nitric oxide or hydrogen peroxide increases the survival of … In immortalised cells
overexpressing of scavenger receptor B1 (SR-… -bound truncated haemoglobin N (Rv1542c) …