… Mice transgenic for HLA-DR3 were more prone to develop AITD than were HLA-DR2 … to
HLA-DR is related to high efficiency in antigen presentation (7). In fact, an exogenous antigen, …

… antigen (HLA) genes have been found to be associated with autoimmune thyroid diseases
(AITD), … of HLA region, it seems to play a prominent role as a molecular background of GD [4]. …

… which encode for the HLA antigens class I (A, B, C) and class II (DP, DQ, DR) [21]. Whereas
… role of HLA class I-mediated response in Graves’ disease, a condition long considered HLA …

… HLA polymorphisms and GD. Accordingly, in the present study, the objective was to identify
HLA … HLA alleles and the risk of Graves’ ophthalmopathy among Iranian GD patients. …

… genes for HLA-DQ antigen, respectively) are expressed in antigen-… II antigens present
extracellularly processed peptide antigens to … Because the antigen-binding groove of MHC class II …

… leukocyte antigen (HLA) class I presents viral antigens … HLA class I normally presents
peptides from intracellular host proteins. During viral infections, HLA class I presents viral antigens …

… of the disease involves the human leukocyte antigen (HLA) … Graves' disease. Further, we
present original pilot results from a cohort of Czech Graves' disease patients regarding the HLA …

… antigen … HLA antigens can bind to antigens and contain disease-related key amino acid
residues, whose changes can affect the characteristics of the interaction between HLA antigens …

… They reported that predisposition to severe GO can be related to a presence of HLA-DR14
and DQ1 antigens, while HLA-B35, B54, DR4, and DQ4 were postulated to play a protective …

… plays a major role in the development of thyroid diseases. Many susceptibility loci associated
with autoimmunity (human leukocyte antigen [HLA], protein tyrosine phosphatase, non-…