Modified methacrylate hydrogels improve tissue repair after spinal cord injury

A Hejčl, J Růžička, K Kekulová, B Svobodová… - International journal of …, 2018 - mdpi.com
… physical properties, or in combination with stem cells [22,23,24,25]… In this study we wanted
to assess the long-term effect of … hydrogels in our study led to motor function improvement. We …

Soft hydrogels with double porosity modified with rgds for tissue engineering

B Podhorská… - Macromolecular …, 2024 - Wiley Online Library
… The dual porosity of hydrogels slightly improved rMSCs … of mesenchymal stem cells (rMSCs)
on the hydrogel surface. … seeded cells, approximately 90% of the cells adhered outside the …

A new three dimensional biomimetic hydrogel to deliver factors secreted by human mesenchymal stem cells in spinal cord injury

I Caron, F Rossi, S Papa, R Aloe, M Sculco, E Mauri… - Biomaterials, 2016 - Elsevier
… Finally, we demonstrate that an improved combination as … We first seeded hMSCs into HG
RGD and we measured the … of a cellular wellness that can contribute to the long term survival. …

The effect of iPS-derived neural progenitors seeded on laminin-coated pHEMA-MOETACl hydrogel with dual porosity in a rat model of chronic spinal cord injury

J Ruzicka, N Romanyuk, K Jirakova… - Cell …, 2019 - journals.sagepub.com
… In our latest study, we compared human bone marrow mesenchymal stem cells (MSCs) and
… any conclusions about the functional outcome. We observed a trend in improvement in 75% …

Biomimetic modification of dual porosity poly (2-hydroxyethyl methacrylate) hydrogel scaffolds—Porosity and stem cell growth evaluation

O Janoušková, M Přádný, M Vetrík… - Biomedical …, 2019 - iopscience.iop.org
… Prior to the seeding of the mouse embryonal stem cells, the … mesenchymal stem cells or
induced pluripotent stem cells [36, … H1[+] were significantly better for cell adhesion and growth (…

Natural biomaterials and mesenchymal stem cells in regeneration of spinal cord injury

K Kekulová - 2019 - dspace.cuni.cz
… The combination of hydrogels with mesenchymal stem cells … (MSCs) was used in a study
of eight patients with chronic … -ECM hydrogel seeded with hWJ-MSCs (n = 4) the hydrogels

Heterogeneous pHPMA hydrogel promotes neuronal differentiation of bone marrow derived stromal cells in vitro and in vivo

O Rybachuk, N Savytska, E Pinet… - Biomedical …, 2023 - iopscience.iop.org
… approaches for seeding stem cells into a heteroporous matrix hydrogel/NeuroGel. In …
HPMA-RGD hydrogels seeded with mesenchymal stem cells improve functional outcome in chronic

Biomaterials and magnetic stem cell delivery in the treatment of spinal cord injury

Š Kubinová - Neurochemical Research, 2020 - Springer
… as mesenchymal stem cells (MSCs) or neural precursors, on the hydrogel surface, but also
improves … Nevertheless, despite various modifications or seeding with different cell types, we …

[HTML][HTML] Mesenchymal stem cells in treatment of spinal cord injury and amyotrophic lateral sclerosis

E Sykova, D Cizkova, S Kubinova - … in cell and developmental biology, 2021 - frontiersin.org
… SCI still results in severe or irreversible loss of function. … SCI + hydrogel + mesenchymal
stem cells (MSCs): spinal cord … MSC-seeded HPMA-arginine–glycine–aspartic acid hydrogel

The role of mesenchymal stromal cells in spinal cord injury

P Jendelova, L Machova‐Urdzikova… - … of Mesenchymal Cells, 2016 - Wiley Online Library
… a statistically significant improve ment in rats implanted with HPMA-RGD hydrogels
HPMA-RGD hydrogels seeded with mesenchymal stem cells improve functional outcome in chronic