… retinoids to select enzymes and receptors by protein-protein … Liver serves as the major site
of vitamin A storage as RE, … ’s delivery of retinol in an environment of numerous enzymes. …

… metabolism and function of retinol, retinal and retinoic acid, … binding pocket exists as a closed
cavity completely isolated … Based on rat liver retinol concentrations, the K m values of liver …

… retinoids in the aqueous cellular medium, and allow retinoid … In extra-hepatic tissues, Crbp1
sequesters retinol transferred into … Isolation of retinoids from the cellular milieu within Crbp1 (…

… distribute hepatic vitamin A stores to extrahepatic tissues. In particular, binding of RBP4 to
‘stimulated by retinoic … crystal structure of human retinol-free RBP4 isolated from serum, urine, …

… by retinol and retinoic acid and inversely correlates with liver … At the ER, these retinol:cellular
retinol-binding protein … enzymes has been identified to be expressed in various liver …

… Specific binding proteins for both retinol and retinoic acid have … in hepatic retinoid metabolism,
the question of how retinoid … and binding proteins in isolated rat liver cells. J Biol Chem …

… from the liver as retinol bound to retinol-binding protein (… all of retinoid storage and metabolism
is that retinoic acid levels … that RBP4 protein or Rbp4 mRNA present in isolated HSCs …

… retinol levels, which may reduce retinoic acid in the liver. This, … the liver, where it is bound to
retinol binding protein (RBP). … each enzyme contribution is a key factor in retinoid metabolism…

… Hepatic retinol and retinol binding protein 4 (RBP4) levels were … (C) Freshly isolated and
4-hour attached primary rat … hepatic levels of the various retinoids (retinyl esters, retinol …

… numerous specialized retinoid-transport proteins, receptors, and enzymes. … hepatic pool of
retinoids requires the hydrolysis of REs, transport of ROL back to the hepatocytes, and binding …