… understanding of CD8 T cell differentiation upon acute … and epigenetic regulation of cell fate
decision and memory formation. … heterogeneity of memory subsets, and enable memory CD8 …

… in the field of memory CD8 + T-cell differentiation, and we will … basis of CD8 + T lymphocyte
heterogeneity, the timing of cell fate decisions, and the epigenetic networks controlling T-cell …

… highlights how heterogeneity of T cell responses can propagate from variation in expression
of a single chemokine receptor or subtle cell positioning all the way to differentiation fate. …

… Similar pronounced cell-fate … memory CD8 T cells to influenza and cytomegalovirus (CMV)
that the authors did not even attempt to put a number on the total range of memory CD8 T-cell …

… ), has the potential to differentiate into long-lived memory CD8 T (Tmem) cells. Some SLECs
… suggested to regulate early Teff cell differentiation and Teff versus Tmem cell fate decisions. …

… Indeed, we show that heterogeneity within DC … to T-cell fate decisions in vivo. While this is
a beneficial approach to understand the induction of chemokine ligands in different cell types, …

… regulation of effector and memory CD8 + T-cell fate determination, … , activated CD8 + T cells
form a heterogeneous effector … CD8 + T cells acquire a terminally differentiated effector state …

… commitment of effector vs memory CD8 + T cell subsets have … Although the mechanisms of
CD8 + T cell fate decision have … the heterogeneity of numerous constellation of T cell subsets, …

… Stem-cell-like features of central memory CD8 T cells. (A) A single naive precursor … As
we have highlighted in this review, single T-cell fate mapping in vivo has provided us with rich …

… phase exhibit substantial phenotypic heterogeneity, which correlates with different potentials
for terminal differentiation or developing into specific memory CD8 T-cell subclasses during …