Multivalent gold nanoparticlepeptide conjugates for targeting intracellular bacterial infections

R Chowdhury, H Ilyas, A Ghosh, H Ali, A Ghorai… - Nanoscale, 2017 - pubs.rsc.org
… -VG16KRKP can penetrate host epithelial and macrophage … the concentration of peptides
in the reaction solution plays a … LPS is known to form homogeneous aggregates of high …

Biomedical applications of the peptide decorated gold nanoparticles

A Rai, L Ferreira - Critical Reviews in Biotechnology, 2021 - Taylor & Francis
… or the orientation of conjugated peptides, which facilitates … microenvironments (eg fibroblasts,
macrophages, and vasculatures) did … that the immunological response of peptide (CLPFFD, …

Recent developments in antimicrobial-peptide-conjugated gold nanoparticles

U Rajchakit, V Sarojini - Bioconjugate chemistry, 2017 - ACS Publications
… cells, fibroblasts, and macrophages) at the same cytotoxic … was conjugated to gold
nanoparticles in a one-step reaction in … is the most desirable in terms of product homogeneity. The …

Synthesis and immunogenicity assessment of a gold nanoparticle conjugate for the delivery of a peptide from SARS-CoV-2

S Farfán-Castro, MJ García-Soto… - … , Biology and Medicine, 2021 - Elsevier
reaction to bind the primary amine of the S 461-493 peptide … to enhance the immunogenicity
of the S 461-493 peptide. An … 461-493 IgM response revealed an increase of this antibody …

Tumor targeting by peptide-decorated gold nanoparticles

B Albertini, V Mathieu, N Iraci… - Molecular …, 2019 - ACS Publications
… is the conjugation of doxorubicin with an RGD-like peptide (… based on the use of gold
nanoparticles (AuNPs) decorated with … The reaction mixture was maintained under magnetic …

Surface functionalization of gold nanoparticles for targeting the tumor microenvironment to improve antitumor efficiency

KF Tan, LLA In, P Vijayaraj Kumar - ACS applied bio materials, 2023 - ACS Publications
… (77) However, to exhibit homotypic ability, a homogeneous … , there will not be any immunogenic
response toward the AuNPs. … targeting peptide-conjugated AuNPs were able to increase

Impact of gold nanoparticles on the functions of macrophages and dendritic cells

AK Dey, A Gonon, EI Pécheur, M Pezet, C Villiers… - Cells, 2021 - mdpi.com
… We found that AuNPs did not activate the BMDCs by themselves but increase the response
of BMDCs to LPS. This finding is consistent with previous studies showing the increased …

Highly stable gold nanoparticle-antigen conjugates with self-adjuvanting property for induction of robust antigen-specific immune responses

ZY Lin, YH Chen, YW Wu, MC Chen - Colloids and Surfaces B …, 2022 - Elsevier
… of macrophages but also a carrier to deliver the conjugatedconjugation of antigens onto
the GNP surface could increaseresponses because of their ability to bind antigenic peptides

Simultaneous stabilization and functionalization of gold nanoparticles via biomolecule conjugation: Progress and perspectives

JW Lee, SR Choi, JH Heo - ACS Applied Materials & Interfaces, 2021 - ACS Publications
… (B) Silencing of enhanced green fluorescent protein … peptide-functionalized gold nanoparticles.
Transmission electron microscopy (TEM) images show the different structures of peptide–…

Gold nanoparticles: multifaceted roles in the management of autoimmune disorders

K Koushki, S Keshavarz Shahbaz, M Keshavarz… - Biomolecules, 2021 - mdpi.com
… mild inflammatory reaction via a small increase in inflammatory … Whereas the macrophages
could not identify either peptide … indicated that GNPs conjugated with aptamers enhanced the …