… and leads to rapid release of the siRNA and drug cargo. (13) … obtained from Integrated DNA
Technologies for quantitative real-… the standard L2000·siRNA lipoplex prepared according to …

… for siRNA is related to the easy synthesis of siRNA molecules… will rapidly release their cargo
from cytoplasmic-endosomes. … Its use in combination with cationic lipids to form lipoplexes (…

… anionic nucleic acids such as plasmid DNA (pDNA) or small-interfering RNA (siRNA). As an
… polyplex stability, efficient uptake, endosomal escape, and cargo release into the cytosol is …

… drugs mainly focuses on plasmid DNA (pDNA), messenger … that of lipoplexes formed by
DOTAP/DOPE and siRNA tends to … , the cargo easily leaks from the CP-siRNA complexes due to …

… were able to efficiently bind siRNA and plasmid DNA (pDNA) … and morphologies of the siRNA
and pDNA complexes of the … efficacy of the exogenesis siRNA and pDNA could be greatly …

… The safe and efficient delivery of siRNA specifically to target … have relied on modified
viruses, which – while very efficient – … with siRNA than DNA cargo (N/P3 vs N/P8, respectively). …

… displayed great siRNA encapsulation and delivery efficiency [61]… Recent studies have reported
the direct fusion of lipoplexes (… location-dependent, but cargo (DNA) size-independent (21 …

… during intracellular DNA delivery mediated by lipoplex and … More interestingly, knockdown
efficiency of both lipoplex and … Consequently, the majority of the internalized cargo will be …

… siRNA lipoplexes based on 17c alone were not very efficient, but … to its specific cargo.
Moreover, 1:1 and 1:2 17c/Chol-based lipoplexes could reach the knockdown efficiency of their …

… After several attempts to reduce the charges of lipoplexes [14,15… have been used to
encapsulate siRNA or DNA in nanogels. These nanogels obtained by ionic gelation allow an efficient …