… semiphysiological model) after vinflunine administration show a … renal impaired patients, the
risk is 42.1% when vinflunine is … intravenous vinflunine that may help drive dose adjustment. …

… the disease control rate (DCR). This was defined by complete response (CR) + partial response
(PR) + stable disease (SD) for both vinflunine-… patients with PS2 and/or renal impairment …

… 0.9% or glucose 5%) via intravenous infusion over 20 min. … The Modification of Diet in Renal
Disease (MDRD) formula … emptive management of constipation are required for vinflunine to …

… Patients with or without renal impairment had a 12-month OS … 63% among patients with
an Eastern Cooperative Oncology … to compare outcomes in patients receiving vinflunine with …

… is commonly administered as a 20-minute intravenous (IV) … 33 patients with renal impairment
received IV vinflunine with … to cytotoxic regimens, might achieve disease control with a more …

… schedule for VFL is an intravenous infusion of 320 mg/m 2 … Performance Score, past irradiation,
renal impairment or age >… VFL application in patients with disease control after first-line …

… , vinorelbine, vindesine and vinflunine) are a class of … intravenously as vincristine sulfate,
which is a vesicant. After … guidelines for the management of VIPN in this setting of patients, and …

… are recommended in patients with renal dysfunction. … is administered intravenously or
intrathecal for the treatment/… newer compound of this family, vinflunine. The only reported adverse …

… care in the management of urothelial cancer and highlight recent … , and strategies such as
intravenous (IV) hydration or … against best supportive care was vinflunine, which showed an …

… both three times a week via intravenous route. The liposome … the most effective treatment
group and vehicle control in 786-… vinflunine have been tested in several clinical trials including …