Tear opiorphin levels in ocular pain caused by corneal foreign body

S Ozdogan, C Sonmez, D Yolcu, M Gungormus - Cornea, 2020 - journals.lww.com
… stimulation and exert a potent antinociceptive effect. However, the … endogenous opioid-dependent
transmission, opiorphinOpiorphin is a naturally occurring human peptide that protects …

[HTML][HTML] Expression of salivary immunoglobulins and their association with analgesic neuropeptide opiorphin in anorexia nervosa during adolescence

E Paszynska, A Hernik, A Slopien, Y Boucher… - Journal of Eating …, 2022 - Springer
… Specifically, their modulation may affect melanocortin four receptor … The levels of the
antinociceptive and inflammatory … Exploring the nature of this relationship might be interesting …

[HTML][HTML] New perspectives in the pathophysiology and treatment of pain in patients with dry eye disease

G Giannaccare, C Ghelardini, A Mancini… - Journal of Clinical …, 2021 - mdpi.com
Human opiorphin is an endogenous pentapeptide with modulatory capabilities of opioid
signaling pathways. It … This suggests that opiorphin may play a role in the modulation of orofacial …

A Novel Ophthalmic Solution Containing Glicopro® Complex for the Treatment of Patients with Dry Eye Disease: Results from a Pilot Study

G Giannaccare, S Vaccaro, M Borselli, C Rossi… - Journal of Clinical …, 2024 - mdpi.com
Human Opiorphin, a natural antinociceptive modulator of … Identification of human
opiorphin, a natural antinociceptive modulator of opioid dependent pathways. Med. Sci. …

Investigating the role of opiorphin genes in prostate cancer and the possible genetic mechanisms by which they modulate tumor growth and androgen-sensitivity.

A Mukherjee, A Park, L Wang, KP Davies - 2020 - researchsquare.com
… both in the modulation of genetic pathways involved in both … dual ectopeptidase inhibitor
with antinociceptive properties. … effect of human opiorphin via opioid-dependent pathways in …

Effects of a Novel Ophthalmic Solution Containing Glicopro® Complex on Signs and Symptoms of Patients with Dry Eye Disease

G Giannaccare, S Vaccaro, M Borselli, GC Scalzo… - 2023 - researchsquare.com
Human Opiorphin, a natural antinociceptive modulator of opioid-dependent pathways. Proc
… Identi cation of human opiorphin, a natural antinociceptive modulator of opioiddependent …

In situ mucoadhesive-thermosensitive liposomal gel as a novel vehicle for nasal extended delivery of opiorphin

P Mura, N Mennini, C Nativi, B Richichi - European Journal of …, 2018 - Elsevier
Opiorphin is a natural peptide recently isolated from human saliva [1], that shows a strong
Human opiorphin, a natural antinociceptive modulator of opioid-dependent pathways

Is there a link between stress and immune biomarkers and salivary opiorphin in patients with a restrictive-type of anorexia nervosa?

E Paszynska, M Roszak, A Slopien… - The World Journal of …, 2020 - Taylor & Francis
Modulation of opiorphin by chronic stress was not confirmed. Unchanged sAA indicates a
partial adaptation of human organism to severe condition during malnutrition. …

[HTML][HTML] Evaluation of Salivary Opiorphin, pH and Flow Rate in Oral Submucous Fibrosis-A Case-Control Observational Study

KS Varsha, KC Lakshmi, A Ganesan… - Journal of Pharmacy …, 2023 - journals.lww.com
… This study was a pilot evaluation of salivary opiorphin in OSMF. Salivary … Human Opiorphin,
a natural antinociceptive modulator of opioid-dependent pathways. Proceedings of the …

Identifying receptors for neuropeptides and peptide hormones: Challenges and recent progress

MSR Abid, S Mousavi, JW Checco - ACS chemical biology, 2021 - ACS Publications
… they act as key modulators of physiological processes such … rationally design drug molecules
targeting these pathways. … known receptors, such as natural products or toxins. Recent …