Human T cell leukemia virus type 1: persistence and pathogenesis
CRM Bangham - Annual review of immunology, 2018 - annualreviews.org
Human T cell leukemia virus type 1 (HTLV-1), also known as human T lymphotropic virus
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related
lentivirus HIV-1, HTLV-1 causes disease in only 5–10% of infected people, depending on
their ethnic origin. But whereas HIV-1 infection and the consequent diseases can be
efficiently contained in most cases by antiretroviral drug treatment, there is no satisfactory
treatment for the malignant or inflammatory diseases caused by HTLV-1. The purpose of the …
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related
lentivirus HIV-1, HTLV-1 causes disease in only 5–10% of infected people, depending on
their ethnic origin. But whereas HIV-1 infection and the consequent diseases can be
efficiently contained in most cases by antiretroviral drug treatment, there is no satisfactory
treatment for the malignant or inflammatory diseases caused by HTLV-1. The purpose of the …
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