… Ionic current changes in PeAF led to reduced SR Ca 2+ load and smaller Ca 2+ transients (…
and forward mode currents through Na + /Ca 2+ exchange under the four conditions (Fig 2D). …

… LV myocardium from patients with sinus rhythm and patients … with impaired Ca 2+ handling,
prolonged action potentials, … human model, we used human iPSC-CM for chronic AF-…

… model with Ca 2+ handling to an atrial myocyte affects the action potential under electrical
remodeling due to persistent … a planar wave propagation during sinus rhythm with 10 pulses at …

… incorporate an intermediate level of spatial and temporal complexity with whole-cell action
potential (AP) and Ca 2+ transient simulations. There are several challenges at this level and …

… potential and the concentration gradients for Ca 2+ and Na + , the time course of NCX current
during an action potential is complicated, and simulation models … on atrial action potentials …

… All patients were in sinus rhythm unless otherwise stated, and were taking a variety of drug
… were fit to detailed data from a single laboratory, the intracellular Ca 2+ handling system …

… and apamin caused larger action potential prolongation in cAF- … improved human atrial
cardiomyocyte computational model … in right atrial (RA)-cardiomyocytes from sinus rhythm control (…

… to CDA on arrhythmia vulnerability in 3D models of the human atria incorporating both …
Two human atrial action potential models were used to simulate membrane kinetics: ALT …

… fibrillation (AF) and to maintain sinus rhythm. However, it has been hypothesized that the …
absence of action potential duration (APD) and the aERP prolonging effect of K Ca 2 inhibition. …

… Ca 2+ current (I CaL ) reduction observed in isolated right … -Nattel (CRN) model of human
atrial action potentials (APs) was … These cell models for sinus rhythm (SR) and CAF were then …