Profibrotic, electrical, and calcium-handling remodeling of the atria in heart failure patients with and without atrial fibrillation
CE Molina, IH Abu-Taha, Q Wang… - Frontiers in …, 2018 - frontiersin.org
… sinus rhythm controls with normal LV function (Ctl) using western blot in right-atrial tissue,
sharp-electrode action potential … in this model and the significantly increased SR Ca 2+ load …
sharp-electrode action potential … in this model and the significantly increased SR Ca 2+ load …
[HTML][HTML] Inhibition of adenosine pathway alters atrial electrophysiology and prevents atrial fibrillation
… obtained from 11 patients in sinus rhythm (SR) undergoing … However, minor changes were
detected on the action potentials … humans, so that rodents can be considered a valid model for …
detected on the action potentials … humans, so that rodents can be considered a valid model for …
Calcium-activated potassium channels inhibition in autonomically stimulated human atrial myocytes
… the action potential (AP) of autonomically stimulated human … Of note, this study focused on
patients in sinus rhythm, where … Bers “Human Atrial Action Potential and Ca2+ Model: Sinus …
patients in sinus rhythm, where … Bers “Human Atrial Action Potential and Ca2+ Model: Sinus …
Human Atrial Cell Models to Analyse the Effect of Extracellular Calcium on Action Potential Duration
… We have analyzed three human atrial cell models (hAM) by testing benchmarks like AP, ICaL,
… Human atrial action potential and Ca2+ model: Sinus rhythm and chronic atrial fibrillation. …
… Human atrial action potential and Ca2+ model: Sinus rhythm and chronic atrial fibrillation. …
Atrial fibrillation: therapeutic potential of atrial K+ channel blockers
U Ravens, KE Odening - Pharmacology & Therapeutics, 2017 - Elsevier
… in a mathematical model of the human atrial action potential (AP… human atria from patients
in sinus rhythm or paroxysmal … -paced dog model of atrial fibrillation, the amplitudes of Ca 2+ -…
in sinus rhythm or paroxysmal … -paced dog model of atrial fibrillation, the amplitudes of Ca 2+ -…
Human atrial fibrillation and genetic defects in transient outward currents: mechanistic insights from multi-scale computational models
G Alrabghi, Y Liu, W Hu… - … Transactions of the …, 2023 - royalsocietypublishing.org
… One important potassium current is the Ca 2+ -independent transient outward K + channel …
[24] model of the human atrial cell predicted abbreviation of action potential duration (APD) by …
[24] model of the human atrial cell predicted abbreviation of action potential duration (APD) by …
[HTML][HTML] A computational framework for testing arrhythmia marker sensitivities to model parameters in functionally calibrated populations of atrial cells
MR Vagos, H Arevalo, BL de Oliveira… - … Journal of Nonlinear …, 2017 - pubs.aip.org
… human atrial cell model to create two populations, representing normal Sinus Rhythm (nSR)
and chronic Atrial Fibrillation … of cardiac arrhythmias is the adaptation of action potential (AP) …
and chronic Atrial Fibrillation … of cardiac arrhythmias is the adaptation of action potential (AP) …
Ca2+/calmodulin-dependent kinase II-dependent regulation of atrial myocyte late Na+ current, Ca2+ cycling, and excitability: a mathematical modeling study
… Ca 2+ -release channel (RyR2)] were incorporated into an existing well-validated computational
model of the human atrial action potential… from human atrial myocytes in a sinus rhythm …
model of the human atrial action potential… from human atrial myocytes in a sinus rhythm …
[PDF][PDF] The role of il-1β on atrial fibrillation physiopathology
O Moreno-Loaiza, AR de Yurre Guirao, N Vera-Nuñez… - Biophysical …, 2020 - cell.com
… Atrial action potential (AP) and Ca2+ transients were … this hierarchical model to suggest
reasons for the variability. Our … to heart rhythm can precipitate the arise of cardiac pathologies …
reasons for the variability. Our … to heart rhythm can precipitate the arise of cardiac pathologies …
[HTML][HTML] Cardiac Excitation and Contraction: Transient outward K+ current can strongly modulate action potential duration and initiate alternans in the human atrium
… Evaluation of the effects of premature stimulation on the human atrial action potential (AP)
waveforms in sinus rhythm (SR) conditions. In the SR baseline model, Ca 2+ -independent …
waveforms in sinus rhythm (SR) conditions. In the SR baseline model, Ca 2+ -independent …