Human eggs, zygotes, and embryos express the receptor angiotensin 1-converting enzyme 2 and transmembrane serine protease 2 protein necessary for severe …

SK Rajput, DM Logsdon, B Kile, HJ Engelhorn… - F&s Science, 2021 - Elsevier
Objective To study messenger ribonucleic acid (mRNA) and protein expressions of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry receptors (angiotensin 1-
converting enzyme 2 [ACE2] and CD147) and proteases (transmembrane serine protease 2
[TMPRSS2] and cathepsin L [CTSL]) in human oocytes, embryos, and cumulus (CCs) and
granulosa cells (GCs). Design Research study. Setting Clinical in vitro fertilization (IVF)
treatment center. Patients Patients undergoing IVF were treated at the Colorado Center for …
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