The role of human host genetics in tuberculosis resistance
… Here we review the current standing of the TB host genetics field ( Figure 1 ). The
epidemiological observations which first suggested the involvement of human genetics in TB …
epidemiological observations which first suggested the involvement of human genetics in TB …
The genetics of susceptibility to tuberculosis: progress and challenges
AA Rudko, EY Bragina, VP Puzyrev… - Asian Pacific Journal of …, 2016 - Elsevier
… human genetic research[4,6]. Among other infectious disease, TB is one of the most actively
studied by geneticists and this is due to several reasons: proven influence of heredity in its …
studied by geneticists and this is due to several reasons: proven influence of heredity in its …
[HTML][HTML] Genomics of human pulmonary tuberculosis: from genes to pathways
CM Stein, L Sausville, C Wejse, RS Sobota… - Current genetic …, 2017 - Springer
… Therefore, in this review, we take a pathway approach to dissecting the host genetics of TB
in … , both human genetic and MTB genetic variation have roles in the global distribution of TB. …
in … , both human genetic and MTB genetic variation have roles in the global distribution of TB. …
Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives
… have started to reveal human vulnerabilities against tuberculosis. In this Review, we present
a perspective on tuberculosis host genomics, based in part … Human genetics of tuberculosis …
a perspective on tuberculosis host genomics, based in part … Human genetics of tuberculosis …
Genetics and evolution of tuberculosis pathogenesis: New perspectives and approaches
ML McHenry, SM Williams, CM Stein - Infection, Genetics and Evolution, 2020 - Elsevier
… human genetics can play in TB disease, especially severity. Severity of TB is at present the
only way to study putative co-evolution between MTB and humans as it is impossible in the …
only way to study putative co-evolution between MTB and humans as it is impossible in the …
[HTML][HTML] Human genetic background in susceptibility to tuberculosis
… infected with Mycobacterium tuberculosis (MTB) will develop clinical disease. The human
genetic factors contributing to susceptibility or resistance to TB pathogenesis have been …
genetic factors contributing to susceptibility or resistance to TB pathogenesis have been …
Mycobacterium tuberculosis complex and human coadaptation: a two-way street complicating host susceptibility to TB
… The main causative agents of TB in humans are phylogenetically similar bacilli called
Mycobacterium tuberculosis (M.tb), Mycobacterium … Human genetics of mycobacterial disease …
Mycobacterium tuberculosis (M.tb), Mycobacterium … Human genetics of mycobacterial disease …
[HTML][HTML] Human genetics of mycobacterial disease
M Dallmann-Sauer, W Correa-Macedo, E Schurr - Mammalian Genome, 2018 - Springer
… background for the eventual outcome of mycobacterial infection, mainly TB and … of human
genetic predisposition to clinical TB disease and leprosy. We also summarize initial genetic …
genetic predisposition to clinical TB disease and leprosy. We also summarize initial genetic …
[HTML][HTML] Genetic Resistance to Mycobacterium tuberculosis Infection and Disease
… Heritability, genetic epidemiology, and population genetic studies have made significant
contributions to reveal the role of human genetic variation in susceptibility to TB infection. The …
contributions to reveal the role of human genetic variation in susceptibility to TB infection. The …
The monogenic basis of human tuberculosis
S Boisson-Dupuis - Human genetics, 2020 - Springer
… Mycobacterium tuberculosis go on developing clinical disease. The contribution of human
genetics to TB pathogenesis has been amply documented by means of classic genetics since …
genetics to TB pathogenesis has been amply documented by means of classic genetics since …