Cancer-Associated Fibroblasts Promote Angiogenesis of Hepatocellular Carcinoma by VEGF-Mediated EZH2/VASH1 Pathway

B Huang, M Huang, Q Li - Technology in cancer research & …, 2019 - journals.sagepub.com
… and metastasis. Meanwhile, HCC is a highly vascularized tumor, 8 so it is critical to study its
… We also found that the inhibition of EZH2 could inhibit the proliferation and angiogenesis of …

The long non-coding RNA MALAT1 promotes the migration and invasion of hepatocellular carcinoma by sponging miR-204 and releasing SIRT1

Z Hou, X Xu, L Zhou, X Fu, S Tao, J Zhou… - Tumor …, 2017 - journals.sagepub.com
critical to continue studies on the molecular mechanisms regulating HCC metastatic behavior
to benefit novel therapeutics targeting … lncRNA releases the inhibition on miRNA targets. To …

[HTML][HTML] An evolving paradigm of cancer stem cell hierarchies: therapeutic implications

AJ Cole, AP Fayomi, VI Anyaeche, S Bai… - Theranostics, 2020 - ncbi.nlm.nih.gov
… , cancer recurrence, and metastasis. The differentiation … hierarchies will identify critical
therapeutic targets to improve … 70) 23 Patients with metastatic hepatocellul ar, pancreatic or …

MicroRNA-302a-3p suppresses hepatocellular carcinoma progression by inhibiting proliferation and invasion

Y Ye, Y Song, J Zhuang, G Wang, J Ni… - OncoTargets and …, 2018 - Taylor & Francis
… by its high rate of distant metastasis and tumor recurrence, even … targeted mRNAs. Citation6
By modulating RNA modification and protein translation, microRNAs are considered critical

Tissue-and serum-associated biomarkers of hepatocellular carcinoma

R Chauhan, N Lahiri - Biomarkers in cancer, 2016 - journals.sagepub.com
… It also inhibits metastasis by stimulating miRNA-200 and inducing histone acetylation. …
strong promise as molecular targets for the development of anti-metastatic vaccines or drugs. For …

Artesunate Sensitizes human hepatocellular carcinoma to sorafenib via exacerbating AFAP1L2-SRC-FUNDC1 axis-dependent mitophagy

Z Ma, W Chen, Y Liu, L Yu, X Mao, X Guo, F Jiang… - Autophagy, 2024 - Taylor & Francis
… to play a critical role in the regulation of cell proliferation, survival, invasion, metastasis, and
… the expression of AFAP1L2 protein and inhibited the phosphorylation of SRC and FUNDC1 …

NRF1 or NRF2: Emerging role of redox homeostasis on PERK/NRF/autophagy mediated antioxidant in tumor and patient dependent chemo sensitivity

S Dastghaib, SM Shafiee, F Ramezani, N Ashtari… - 2024 - preprints.org
… can facilitate tumor invasion and metastasis, contributing to … 78 kDa; HIF1α, Hypoxia inducible
factor ; HSPA5, Heat shock … In a study, the inhibition of the critical autophagy gene Atg7 …

[HTML][HTML] Mechanisms of primary and acquired resistance to immune checkpoint inhibitors in patients with hepatocellular carcinoma

S De Lorenzo, F Tovoli, F Trevisani - Cancers, 2022 - mdpi.com
… that is a key signalling node and a regulator of the critical … , tumour progression and metastasis
has been reported in … been a target for HCC drugs for a long time, since its inhibition leads …

[PDF][PDF] MicroRNA-22 suppresses metastasis by targeting SNAI1 in the ovarian cancer cell line SKOV-3

R Zhang, W Shi, Z Chen, L Li, H Liu, X Huang, Z Liu… - Int J Clin Exp …, 2019 - e-century.us
… that miR-22 inhibited metastasis. A bioinformatic analysis … Metastasis is a crucial step
in the process of tumorigenesis. One … miRNA delivery: emerging therapy for hepatocellular …

LncRNA MIR210HG facilitates non-small cell lung cancer progression through directly regulation of miR-874/STAT3 axis

L Bu, L Zhang, M Tian, Z Zheng, H Tang… - Dose …, 2020 - journals.sagepub.com
… Additionally, the role of miR210HG in NSCLC metastasis and other processes have not …
inhibited NSCLC cell proliferation in vitro. In addition, miR210HG knockdown inhibited the …