IL-17A enhances IL-13 activity by enhancing IL-13–induced signal transducer and activator of transcription 6 activation

SL Hall, T Baker, S Lajoie, PK Richgels, Y Yang… - Journal of Allergy and …, 2017 - Elsevier
… Mechanistically, we observe that IL-17A enhances IL-13dependent activation of a key …
BAL fluid concentrations of IL-4, IL-5, IL-9, and IL-10 and total serum IgE concentrations were …

[HTML][HTML] Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes

XW Zhang, S Mi, Z Li, JC Zhou, J Xie, F Hua, K Li… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… We found that IL-17A antagonism suppressed the high expression of TGF-β1, … IL-13 and
IL-10 in fibrotic hepatic tissues, but up-regulated the level of IFN-γ (Figure ​2D). Blocking IL-17A

[HTML][HTML] IL-10 modulates Th17 pathogenicity during autoimmune diseases

B Guo - Journal of clinical & cellular immunology, 2016 - ncbi.nlm.nih.gov
… Th2 cells secrete IL-4, IL-5 and IL-13. TGFβ and IL-6 induce Th17 cells to produce IL-17A
(… The IL-17 cytokine family has at least six members: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (…

IL-25 attenuates rheumatoid arthritis through suppression of Th17 immune responses in an IL-13-dependent manner

D Liu, T Cao, N Wang, C Liu, N Ma, R Tu, X Min - Scientific Reports, 2016 - nature.com
IL-17A, as well as type 2 cytokines, IL-4 and IL-13 2 . To determine whether IL-25 plays a
regulatory role in RA, we first analysed the expression of this cytokine in RA patients. As shown …

Allergen-induced IL-6 regulates IL-9/IL-17A balance in CD4+ T cells in allergic airway inflammation

N Schütze, S Trojandt, S Kuhn, JM Tomm… - The Journal of …, 2016 - journals.aai.org
… (C) IL-10 and IL-21 production was measured from … IL-5/IL-13–producing ILC type 2 to
IL-17A–producing ILC … The observed diminished IL-5/IL-13 production of ILCs in presence of IL-6 …

The expressions of TSLP, IL-33, and IL-17A in monocyte derived dendritic cells from asthma and COPD patients are related to epithelial–macrophage interactions

M Paplinska-Goryca, P Misiukiewicz-Stepien… - Cells, 2020 - mdpi.com
… -4, IL-5, IL-13) and TNF-α but downregulated IL-10 and interferon … , and IL-17A mRNA
expression in moDCs after IL-13 or poly I:… TNF-α mRNA expression in moDCs after IL-13 or poly …

Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps

M Okano, T Fujiwara, S Kariya, T Higaki… - Allergology …, 2016 - jstage.jst.go.jp
… (SEB), following which the levels of IL-5, IL-10, IL-13, IL-17A and interferon (IFN)-g in the …
IL-10 and cyclooxygenase in Poly(IC)-mediated signaling, DNPCs were treated with anti-IL-10

Regulation of filaggrin, loricrin, and involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: pathogenic implications in atopic dermatitis

M Furue - International journal of molecular sciences, 2020 - mdpi.com
… In addition to IL-4 and IL-13, IL-22 and IL-17A are probably … As IL-4, IL-13, IL-22, and IL-17A
are all capable of inducing … IVL expression is regulated by IL-4, IL-13, IL-22, and IL-17A. The …

Increased IL-17A/IL-17F expression ratio represents the key mucosal T helper/regulatory cell-related gene signature paralleling disease activity in ulcerative colitis

Y Iboshi, K Nakamura, K Fukaura, T Iwasa… - Journal of …, 2017 - Springer
… Other Th subsets and their related cytokines, including IL-13, have been shown to … Th17 is
closely associated with the pathophysiology of UC, whereas Th1-related molecules and IL-13

Molecular switches for regulating the differentiation of inflammatory and IL-10-producing anti-inflammatory T-helper cells

D Fang, J Zhu - Cellular and Molecular Life Sciences, 2020 - Springer
… , IL-13 increases IL-10 production but only in polarized Th17 … Although IL-10 is difficult to
be detected in human Th17 cells … Th17 cell clones can produce IL-10, and both IL-10 + IL-17A