Epigenetic regulation of miR-200 as the potential strategy for the therapy against triple-negative breast cancer

JR Mekala, SM Naushad, L Ponnusamy… - Gene, 2018 - Elsevier
… We also discuss the need for identifying novel HDAC … (PR) expression and human epidermal
growth factor receptor 2 (… The over-expression of miR-200a/miR-200b/429 is reported to …

Differential expression and role of miR-200 family in multiple tumors

B Wen, R Zhu, H Jin, K Zhao - Analytical Biochemistry, 2021 - Elsevier
… human breast stem cells and mouse breast stem cells, miR-200b … that overexpression of
miR-200b/c/429 can effectively inhibit … However, The detection of miR-200s in 15 normal ovarian …

miR-9 and miR-200 regulate PDGFRβ-mediated endothelial differentiation of tumor cells in triple-negative breast cancer

E D'Ippolito, I Plantamura, L Bongiovanni, P Casalini… - Cancer research, 2016 - AACR
… organized in two clusters: miR-200a/b/429 and miR-200c/141) … panel of TNBC cell lines,
using miR-200b and miR-200c as … miR-9 expression identified breast cancer patients with poor …

miR‐200c suppresses stemness and increases cellular sensitivity to trastuzumab in HER2+ breast cancer

H Tang, C Song, F Ye, G Gao, X Ou… - Journal of cellular …, 2019 - Wiley Online Library
… isolation and identification of BCSCs in breast cancer tissues … to HER2 overexpression and
stemness enhancement of BCSCs. … Members of the miR-200 family like miR-200b/c/429 can …

[HTML][HTML] Cis-acting super-enhancer lncRNAs as biomarkers to early-stage breast cancer

AS Ropri, RS DeVaux, J Eng, SV Chittur… - Breast Cancer …, 2021 - Springer
Increased breast cancer screening over the past four … have identified differentially expressed
SE-lncRNAs which can … miR-200 family of genes of which miR-200b is well studied to have …

[HTML][HTML] Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses MXRA8 Levels and Impairs Breast Cancer Growth and Metastasis In Vivo

KE Simpson, KL Watson, RA Moorehead - Genes, 2022 - mdpi.com
breast cancer is the miR-200 family. This family consists of five members organized into two
clusters, the miR-200b/200a/429identity; miR-200 family members reduce the expression of …

miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes

R Perdigao-Henriques, F Petrocca, G Altschuler… - Oncogene, 2016 - nature.com
… To identify other miR-200-regulated genes, we isolated … -200’s enhancement of epithelial
gene expression. Candidate … mature miR-200b/c/429 family expression in human breast tumors…

Mechanisms and functions of MiR-200 family in hepatocellular carcinoma

Y Mao, W Chen, H Wu, C Liu, J Zhang… - OncoTargets and …, 2021 - Taylor & Francis
… of the zinc finger enhancer-binding protein family. Studies … miR-200b/200a/429 to
significantly silence the expression of … detection technology, it is impossible to make a long-term

miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance

M Mutlu, U Raza, Ö Saatci, E Eyüpoğlu… - Journal of Molecular …, 2016 - Springer
… In the last two decades, identification of almost 2600 miRNAs in … the miR-200a/b/429 cluster
containing miR-200a, miR-200b, … In addition to four enhancer boxes (E-box 1–4, CAGGTG), …

Characterizing the Function of the miR-200s in Triple Negative Breast Cancer

K Simpson - 2023 - atrium.lib.uoguelph.ca
… Additionally, our studies identified SUZ12 and subsequent … /141 cluster and the miR-200b/200a/429
cluster. We have found … significant increase in miR200b and miR-429 expression as …