Glyceraldehyde-3-phosphate dehydrogenase is a multifaceted therapeutic target

VF Lazarev, IV Guzhova, BA Margulis - Pharmaceutics, 2020 - mdpi.com
Another cause of GAPDH-mediated cell death is protein … Another mechanism triggered
by the oxidation of M46 on the … of cancer cells, and the markers of the epithelial-mesenchymal …

Molecular characterization of glyceraldehyde-3-phosphate dehydrogenase from Eimeria tenella

W Huang, S Zhu, T Chen, Q Zhao, H Dong… - Parasitology …, 2022 - Springer
… was significantly higher in second-generation merozoites than … , a large number of intestinal
epithelial cells of the host are … was identified and transformed into E. coli BL21 competent …

Pleiotropic effects of moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cancer progression, invasiveness, and metastases

MA Sirover - Cancer and Metastasis Reviews, 2018 - Springer
… cancer tissue indicated a relationship between Akt2 p detection … En toto, this study indicates
a second protective effect of … examined as a function of epithelial-mesenchymal transition (…

Moonlighting glyceraldehyde-3-phosphate dehydrogenase: Posttranslational modification, protein and nucleic acid interactions in normal cells and in human …

MA Sirover - Critical Reviews in Biochemistry and Molecular …, 2020 - Taylor & Francis
… were initiated to examine another process. Accordingly, in … resulted in the positive identification
of the protein GAPDH”. The … human ovarian epithelial cells and in ovarian cancer cells. Of …

Glyceraldehyde 3-Phosphate Dehydrogenase on the Surface of Candida albicans and Nakaseomyces glabratus Cells—A Moonlighting Protein That Binds Human …

A Bednarek, D Satala, M Zawrotniak, AH Nobbs… - International Journal of …, 2024 - mdpi.com
… —play predominant roles in mediating adhesion to host epithelial cells [61,62]. The capacity
for … Another issue addressed in the current work concerned the identification of potential …

Lactate dehydrogenase and glycerol-3-phosphate dehydrogenase cooperatively regulate growth and carbohydrate metabolism during Drosophila melanogaster …

H Li, M Rai, K Buddika, MC Sterrett, A Luhur… - …, 2019 - journals.biologists.com
… catabolism, glyceraldehyde-3-phosphate dehydrogenase (… of animal development can
identify the metabolic mechanisms that … by feeding 13 C 6 -glucose to second instar (L2) larvae. …

Glyceraldehyde-3-phosphate dehydrogenase restricted in cytoplasmic location by viral GP5 facilitates porcine reproductive and respiratory syndrome virus replication …

X Liu, X Liu, J Bai, Y Gao, Z Song, H Nauwynck… - Journal of …, 2021 - Am Soc Microbiol
… To identify the domains critical for the binding of GP5 to GAPDH, … -145 cells (an African green
monkey kidney epithelial cell line… For another experiment, Marc-145 cells were transfected …

Mycobacterium tuberculosis Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Functions as a Receptor for Human Lactoferrin

H Malhotra, A Patidar, VM Boradia, R Kumar… - Frontiers in cellular …, 2017 - frontiersin.org
… One of the identified receptors is the glycolytic enzyme Glyceraldehyde-3-phosphate
dehydrogenase (GAPDH). This … A second wash with SFM was carried out after 24 h of infection …

Glyceraldehyde-3-phosphate Dehydrogenase and Fructose-1, 6-bisphosphatase of the Enteric Pathogens C. jejuni and H. pylori

A Ayna - 2016 - figshare.le.ac.uk
Another finding of the analysis of genomic data is that, C. jejuni lack an Open Reading … of
a glycerol-3-phosphate transporter encoded by GlpT identified in the C. jejuni strain 81–176 (…

Moonlighting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) protein of Lactobacillus gasseri attenuates allergic asthma via immunometabolic change in …

PC Chen, MH Hsieh, WS Kuo, LSH Wu, HF Kao… - Journal of biomedical …, 2022 - Springer
… include adhesion to the host epithelium and modulation of the host … followed by HRP-conjugated
secondary antibodies. Absorbance at … In this study, we identified a novel mechanism of …