… disease is a rare, inherited, neurodegenerative disease. Clear evidence of the therapeutic
efficacy of 2-hydroxypropyl-β-cyclodextrin (HPβCD) in animal models … this study identified CSF …

… We discuss improvements in the detection of … The same is observed in a GD mouse model
with induced GCase … and second most common neurodegenerative disorder, and genetic …

… Alzheimer’s disease (AD) is the most common form of neurodegenerative disease among
older … As such, it is important to identify general principles relating gut flora to AD models. …

… for some of these diseases were more recently identified. For … common neurodegenerative
diseases, infectious diseases, … large and small animal models in which pathogenesis and …

… syndrome, iduronate sulfatase deficiency), and MPS VII (Sly … neurodegenerative diseases
including Alzheimer’s disease … storage of these lipids in the mouse models of MPS IIIA, B, and …

… neurodegenerative disorders and delineated the disease … In 1980 Brady and Pentchev
reported a mouse model with … to continue to identify these new and alternative disease targets. …

… existing therapies, and to identify additional therapeutic targets. … for patients affected by MPS
VII or Sly Syndrome. A phase III trial … neurodegeneration in the MPS IIIC mouse model [65]. …

… , critical milestones in our understanding of the disease, the identification of animal models,
and the evolution of single and multimodal therapies. The superscript numbers associated …

… To identify a neuronal phenotype that could be used to … cells types in a MPS VII mouse model
and in other LSD, such as … other neurodegenerative diseases like Alzheimer’s disease 52 , …

… Impaired GCase activity has been identified also in … of a family history of a neurodegenerative
disorder, therefore, it is … promising results in cellular and animal models. We are now in a …