Immune privilege in corneal transplantation

J Hori, T Yamaguchi, H Keino, P Hamrah… - Progress in retinal and …, 2019 - Elsevier
… of immune privilege that have been elucidated from animal models of ocular inflammation,
especially those involving corneal transplantation, … in local and systemic immune regulation is …

Alloimmunity and tolerance in corneal transplantation

A Amouzegar, SK Chauhan, R Dana - The Journal of Immunology, 2016 - journals.aai.org
corneal transplantation in Foxp3-lineage reporter–transgenic mice to evaluate the pathologic
conversion of Tregs in immune privilege… of corneal immune privilege and allograft rejection. …

[HTML][HTML] Immunology and donor-specific antibodies in corneal transplantation

J Major, B Foroncewicz, JP Szaflik, K Mucha - Archivum Immunologiae et …, 2021 - Springer
… Due to the immune-privileged location, corneal transplantation … -risk corneal transplant
recipients, there are three main factors that abolish immune privilege: vascularization of corneal

[HTML][HTML] Protective role of ICOS and ICOS ligand in corneal transplantation and in maintenance of immune privilege

T Kunishige, H Taniguchi, M Terada… - … & Visual Science, 2016 - iovs.arvojournals.org
… the immune privilege for corneal transplantation. To further clarify the mechanism of immune
privilege for corneal transplantation, … The cornea constitutively expresses various immune-…

[HTML][HTML] Ocular immune privilege and transplantation

AW Taylor - Frontiers in immunology, 2016 - frontiersin.org
… inflammation and promote immune tolerance. There are … the immune-privileged tissue. This
review presents the current understanding of how the mechanism of ocular immune privilege

[HTML][HTML] VISTA is crucial for corneal allograft survival and maintenance of immune privilege

T Kunishige, H Taniguchi, T Ohno… - … & Visual Science, 2019 - tvst.arvojournals.org
… As described above, the present study showed that a mechanism of VISTA-mediated
immune privilege in corneal transplantation is tolerance (ACAID) via splenic CD8 + CD103 + T …

Immune checkpoint inhibitors and corneal transplant rejection: A call for awareness

HS Sandhu, HD Hemmati, R Dana - Immunotherapy, 2020 - Taylor & Francis
… allografts can be transplanted without the need for systemic … of corneal immune privilege
is the immune checkpoint molecule PD-L1. Therein lies the potential for corneal transplant

[HTML][HTML] Immune checkpoints contribute corneal immune privilege: implications for dry eye associated with checkpoint inhibitors

J Hori, T Kunishige, Y Nakano - International journal of molecular …, 2020 - mdpi.com
… ocular inflammation, especially those involving corneal transplantation, it also provides an
update on immune checkpoint molecules in corneal and systemic immune regulation, and its …

[HTML][HTML] Role of immune cell diversity and heterogeneity in corneal graft survival: A systematic review and meta-analysis

J Zhu, T Inomata, A Di Zazzo, K Kitazawa… - Journal of Clinical …, 2021 - mdpi.com
… been introduced to improve corneal graft survival. Conventional … for corneal transplantation
focusing on immune checkpoint … immunotherapies for corneal transplantation were assessed …

[HTML][HTML] Corneal transplantation and immunosuppressants

PN Akkaya, O Erbaş - … Nightingale Journal of Transplantation, 2019 - journaltxdbu.com
… unique immune circumstances in the cornea, cornea transplants … It is true that the cornea is
a tissue with “immune privilege” … not be mistaken with “immune immunity” as the presence of …