… Moreover, these factors modulate the host immune responses to tuberculosis. Studies have
… In this review, we summarize the association of HLA and non-HLA gene polymorphisms in …

… of immune responses against exogenous pathogens. Consequently, it is possible that TLR
gene polymorphisms, … potential associations between TLR gene polymorphisms and TB. …

… genes participate in immune response, and their polymorphism can alter immunity and
lead to genetic … tuberculosis and the genetic polymorphism is the mechanism that leads to …

… between these polymorphisms and tuberculosis susceptibility. … the TLRs gene polymorphism
and susceptibility to tuberculosis. … SNPs is important to investigate immune responses to TB. …

… Tetraspanins also play important roles in cells of the immune system and transfer
immune signals from molecules such as those of CD4, CD8, MHC class I, and MHC class II. …

… of our immune system is the innate immune system which … immune response, was first
identified as a type-1 transmembrane receptor in 1997 as hToll [5]. The antibacterial response of …

… infected with Mycobacterium tuberculosis during their lifetime, … , genetic variations present
in the immune-response genes of … of genetic variations in immune response genes to these …

… Interferon gamma (IFNG) was chosen in this study because of its critical role in the immune
system at multiple levels [12]. IFNG is located in chromosome 12q15, and it has four exons. …

… gene were investigated in Han Chinese patients infected with Mycobacterium tuberculosis
(… associated with susceptibility to tuberculosis or pulmonary tuberculosis. Haplotype analysis …

… factors may play a crucial role in the modulation of immune responses to MTB infection and
in clinical progression of TB. We explained that genetic polymorphisms of the several genes …