… However, this localization, and subcellular mapping is controversial and hampered by limited
antibody reagents that work for immunolocalization, especially for PC1. Consistent with the …

… as representing the number of PC2 punctuate staining per cell in the cluster, for the various
experimental conditions. CaSR was co-immunolocalized with PC2, utilizing specific primary …

… Fibrocystin cleavage products in tissue. In addition, we found that Polycystin-2 fails to co-…
biochemical analyses, immunopurification, and immunolocalization studies. This feature will be …

… Based on biochemical analysis and immunolocalization results, polycystin-1 and polycystin-2
can form a complex that traffics to the primary cilia of kidney collecting duct epithelia (3, 4, 8…

… cyst-lining epithelial cells. Proteins of the basolateral Scribble complex immunolocalized to
the … PKD1 and PKD2, which encode polycystin 1 (PC1) and polycystin 2 (PC2), respectively. …

… polycystin-1-associated G protein signaling contributes to the pathogenesis of polycystic
kidney disease. This review highlights the structural and functional features shared by polycystin…

… In many cases, early descriptions of PC1 expression patterns by Western blot or
immunolocalization using both homemade and commercial PC1 antibodies produced inconsistent …

… of the polycystin-2 channel and the polycystin-1/ polycystin-2 … function of polycystin-1 in the
polycystin-1/polycystin-2 … by Western blot or immunolocalization using both homemade and …

… ADPKD is caused by a mutation in the PKD1 or PKD2 genes that encode polycystin-1 (PC-1)
and polycystin-2 (PC-2), respectively. PC-1 is an important regulator of several signaling …

… 22 23 24 25–26 and immunolocalize to human cystic tubular epithelial cells in ADPKD. It is
… , in human ADPKD kidneys and primary culture ADPKD epithelial cells compared with NHK …