Chimeric antigen receptor T cells in hematologic malignancies

BR Shank, B Do, A Sevin, SE Chen… - … : The Journal of …, 2017 - Wiley Online Library
… not considered first-line immunosuppression because they have … It is unclear if lower doses
or shorter courses of steroids … third generation autologous CAR T cells and allogenic CAR T …

The clinical impact of COVID-19 epidemic in the hematologic setting

C Finelli, S Parisi - Advances in biological regulation, 2020 - Elsevier
… First of all, given the immunosuppressive effect of many … For ALL patients, the use of
glucocorticoids during the prophase… to receive an autologous or allogeneic hematopoietic cell …

The immunosuppressive signature of menstrual blood mesenchymal stem cells entails opposite effects on experimental arthritis and graft versus host diseases

P Luz-Crawford, MJ Torres, D Noël, A Fernandez… - Stem …, 2016 - academic.oup.com
lower amounts of immunosuppressive factors such as IDO, PDL-1, PGE2, and Activin A and
exhibited a substantial lower … Also the therapeutic effect of autologous versus allogeneic use …

Recommendations for managing PD-1 blockade in the context of allogeneic HCT in Hodgkin lymphoma: taming a necessary evil

C Herbaux, R Merryman, S Devine… - Blood, The Journal …, 2018 - ashpublications.org
… are ineligible for autologous hematopoietic cell transplantation (… at a low dose and consider
escalating the dose if there is no … Further immunosuppression should be given promptly if the …

Brentuximab vedotin in combination with or without donor lymphocyte infusion for patients with Hodgkin lymphoma after allogeneic stem cell transplantation

P Tsirigotis, I Danylesko, K Gkirkas… - Bone marrow …, 2016 - nature.com
… exposed to BV for treatment of relapse after autologous-SCT. Ten out of 16 patients …
immunosuppression, and in all cases, GVHD resolved after a short course of low dose steroids

[HTML][HTML] Nonmyeloablative allogeneic hematopoietic cell transplantation

R Storb, BM Sandmaier - Haematologica, 2016 - ncbi.nlm.nih.gov
… Gy TBI either without postgrafting immunosuppression or with … had failed high-dose autologous
or allogeneic HCT or had … (A) Cumulative incidence of use of systemic steroids in arm 1 (…

Allogenic umbilical cord-derived mesenchymal stromal cells sustain long-term therapeutic efficacy compared with low-dose interleukin-2 in systemic lupus …

Z Cao, DD Wang, L Jing, X Wen, N Xia… - Stem Cells …, 2023 - academic.oup.com
… application of glucocorticoids and immunosuppressive agents … lupus nephritis patients
receiving allogeneic umbilical cord … correlated with their immunosuppressive effects. However, …

Safety and preliminary efficacy of allogeneic bone marrow-derived multipotent mesenchymal stromal cells for systemic sclerosis: a single-centre, open-label, dose …

D Farge, S Loisel, M Resche-Rigon… - The Lancet …, 2022 - thelancet.com
… contraindications to conventional immunosuppressive therapy or autologous haematopoietic
stem … monoxide, or both, without additional immunosuppression, except low-dose steroids. …

[HTML][HTML] Culture-expanded mesenchymal stromal cell therapy: does it work in knee osteoarthritis? A pathway to clinical success

G Copp, KP Robb, S Viswanathan - Cellular & Molecular Immunology, 2023 - nature.com
… We examined MSC dose, tissue of origin, and autologous vs. allogeneic origins as well as
patient … [70] groups showed that lower doses of allogeneic MSCs were better (although neither …

[HTML][HTML] The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
… Both allogenic or autologousimmunosuppressive but still can release chemokines for
attracting immune cells. The MHC class II expression in MSCs requires stimulation by a low dose