… and thus the AFR in severe pulmonary arterial hypertension (PAH) may … progressive right
heart failure and death in severe PAH. … (C,D) A 8-mm atrial flow regulator was implanted with …

… Lately, novel implantable atrial communication devices have … Atrial flow regulator (AFR)
device delivered by Occlutech … with severe right ventricular (RV) failure due to pulmonary …

… Implantable atrial flow regulator for severe, irreversible pulmonary arterial hypertension.
EuroIntervention. 2015;11(6):706–9 This paper describes the first in-man implantation of an AFR…

… A novel implantable atrial flow regulator (AFR) made of … a patient with severe irreversible
PAH to provide an atrial septal … of syncope, acute pulmonary hypertensive crisis and death. The …

… by improved blood pressure, right ventricular function, and renal function [Citation5–7].
Table 1 shows a contemporary summary of published studies of atrial flow regulator devices in …

… Due to the patient’s progressive deterioration and lack of alternative medical therapy, the
PAH spe‑ cialist team decided to implant the atrial flow regulator (AFR) to decompress the right …

… (DHMCT), PAH dogs were implanted with IASDs (group A) or … (PAH) is a progressive and
irreversible disorder. Factors … the atrial septum in early pulmonary arterial hypertension (PAH)…

… PAH is an irreversible disease with fatal outcome … (i) syncope due to acute pulmonary
hypertensive episodes after … , and previously implanted atrial septal occluders were exclusions. …

… with heart failure or pulmonary arterial hypertension, the … , before the onset of irreversible
changes in several tissues, … The SM was implanted percutaneously across the atrial septum…

… Atrial flow regulator (AFR) is a device to make an iatrogenic … The AFR was implanted for her
without any complications. Then, … L/m, and pulmonary vascular resistance was 4 wood units. …