Signaling pathways controlling activity-dependent local translation of BDNF and their localization in dendritic arbors

G Baj, V Pinhero, V Vaghi… - Journal of cell …, 2016 - journals.biologists.com
… Translation of a subset of dendritically localized mRNAs in close … we carried out experiments
in which we visualized BDNF mRNA … a BDNF–GFP exon 6 transcript at the same time. This …

[HTML][HTML] Activity-dependent Pre-miR-134 dendritic localization is required for hippocampal neuron dendritogenesis

F Zampa, S Bicker, G Schratt - Frontiers in molecular neuroscience, 2018 - frontiersin.org
… -134 transport to dendrites is regulated by neuronal activity. … of primary cortical neurons
induces transcription of the miR-… sequence motifs within dendritically localized mRNAs are bound …

New frontiers in RNA transport and local translation in neurons

SJ Van Driesche, KC Martin - Developmental neurobiology, 2018 - Wiley Online Library
… of dendritically or axonally localized RNAs in neurons on a … This model of activity-dependent
local mRNA translation is … be difficult for dendritically localized transcripts to encounter all of …

Mechanisms that communicate features of neuronal activity to the genome

DA Heinz, BL Bloodgood - Current Opinion in Neurobiology, 2020 - Elsevier
… mechanisms that drive activity-dependent gene expression … An intriguing example of this
is seen with the dendritically … We have identified a small pool of Npas4 mRNAs, which are …

The travels of mRNAs in neurons: do they know where they are going?

S Das, RH Singer, YJ Yoon - Current opinion in neurobiology, 2019 - Elsevier
… understanding of the kinetics of mRNA transport in the neuron. … relevance to other dendritically
localized mRNAs with varying … to address whether activity-dependent RNA localization …

[HTML][HTML] Is Arc mRNA unique: a search for mRNAs that localize to the distal dendrites of dentate gyrus granule cells following neural activity

CA de Solis, AA Morales, MP Hosek… - Frontiers in Molecular …, 2017 - frontiersin.org
… Our study determined other activity dependent transcripts … detect dendritically localized
mRNAs and the number of mRNAs … which activity dependent genes have their RNAs transported

mRNA trafficking in the nervous system: A key mechanism of the involvement of activity‐regulated cytoskeleton‐associated protein (arc) in synaptic plasticity

M Fila, L Diaz, J Szczepanska, E Pawlowska… - Neural …, 2021 - Wiley Online Library
… a process called activity-dependent Arc mRNA degradation. It … with Arc transcription and
mRNA transport in single neurons … and encapsulation of dendritically localized Arc mRNA, which …

[HTML][HTML] Activity-dependent expression of Channelrhodopsin at neuronal synapses

F Gobbo, L Marchetti, A Jacob, B Pinto, N Binini… - Nature …, 2017 - nature.com
… in an activity-dependent manner and its messenger RNA … to dendrites in an activity-dependent
manner 54 . However, … ), out of the many BDNF transcripts 54 , were much less responsive …

[HTML][HTML] Comprehensive catalog of dendritically localized mRNA isoforms from sub-cellular sequencing of single mouse neurons

SA Middleton, J Eberwine, J Kim - BMC biology, 2019 - Springer
neurons must transport a wide variety of RNAs long distances from their origination point in
the nucleus. Here, we carried out single neuron … of the expressed transcripts were localized, …

Brain‐derived neurotrophic factor‐induced regulation of RNA metabolism in neuronal development and synaptic plasticity

RO Costa, LF Martins, E Tahiri… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
… showed activity-dependent induction of BDNF mRNA by a … to synapse organization or to
the positive regulation of neuron … and synaptic transcripts, by transporting mRNAs to very …