Staphylococcus aureus is a preeminent bacterial pathogen capable of colonizing diverse
ecological niches within its human host. We describe here the pangenome of S. aureus based …

… reconstructions require manual curation and evaluation 101 , and many models introduced
in this review were created automatically or semi-automatically, some models might lack …

… an overall evaluation of the quality of a reconstruction and … , Staphylococcus aureus 88
and Klebsiella pneumoniae 89 . … , reconstruct the entire metabolic network from an annotated …

… A detailed and comprehensive knowledge of staphylococcal metabolism is … reconstructed
and experimentally validated an updated and enhanced genome-scale metabolic model of S…

… In this work, we installed and applied the most promising genome-scale reconstruction
tools to provide a systematic evaluation of their performance and outputs. With each tool we …

… , iEK1101 was used to provide understanding of this pathogen’s metabolic status under …
metabolic flux distributions in the two conditions allowed evaluation of the pathogen’s metabolic …

… and reaction essentiality predictions can then be made and validated against experimental
… metabolism and pathogen virulence. In a study of Staphylococcus aureus, metabolic models …

… (A) Evolution of S. aureus genome scale metabolic reconstructions and their biomass …
modelled protein structures to validate and further guide our reconstruction efforts. The remaining …

… We validated the model qualitatively by demonstrating its accuracy prediction of propionate
and acetate production patterns, which were consistent with experimental observations. …

… Far less studied than Staphylococcus aureus, the … Improving our knowledge of the
metabolic processes that allow S. … curated, genome-scale metabolic model for S. epidermidis …