Quinolizidine alkaloids derivatives from Sophora alopecuroides Linn: Bioactivities, structure-activity relationships and preliminary molecular mechanisms

Y Li, G Wang, J Liu, L Ouyang - European Journal of Medicinal Chemistry, 2020 - Elsevier
… -virus and anti-arrhythmia … activities of quinolizidine alkaloids, as well as the relationship
between biological function and structure-activity of substituted quinolizidine alkaloids. We …

Phytochemical information and biological activities of quinolizidine alkaloids in Sophora: a comprehensive review

H Wang, C Xia, L Chen, J Zhao, W Tao… - Current Drug …, 2019 - ingentaconnect.com
… been made to separate the quinolizidine alkaloids in Sophora. … seed of Sophora flavescens
or the stem and leaf of Sophora … from different parts of Sophora flavescens Ait. by ultra high-…

Alkaloids from the roots of Sophora flavescens and their anti-tumor activity

Y Xu, X Wang, K Sa, H Li, L Chen - Fitoterapia, 2023 - Elsevier
… All obtained alkaloids were tested for their inhibitory activity on MCF-7 cells after 24 h of
treatment at a concentration of 20 μM. The results … Indolizidine and quinolizidine alkaloids

[PDF][PDF] A Review on the chemistry and pharmacological properties of Oxymatrine alkaloid compound obtained from the roots of Sophora flavescens Aiton.

R Shah, P Sharma, N Modi - Bull. Env. Pharmacol. Life Sci, 2021 - researchgate.net
… Oxymatrine- a quinolizidine alkaloid, which is extracted from the … Sophora flavescens. There
are several signalling pathways that have shown effects ofanti-cancer, anti-inflammatory, anti

Matrine, oxymatrine, and compound Kushen injection from the roots of Sophora flavescens: An overview of their anticancer activities

EWC Chan, SK Wong, HT Chan - Journal of Chinese …, 2022 - jcps.bjmu.edu.cn
… Reference was also made on botanical websites, such as … quinolizidine alkaloids from the
roots of Sophora flavescens (… found in the roots of Sophora flavescens Ait. (Kushen) of the …

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
… built from one or two quinolizidines, differentiating them from other alkaloids derived from
the l-… Thus, the nitrogen atoms of the quinolizidine skeleton (C 15 N 2 ) are derived from l-lysine-…

In vitro and in vivo anti-metastatic effect of the alkaliod matrine from Sophora flavecens on hepatocellular carcinoma and its mechanisms

M Dai, N Chen, J Li, L Tan, X Li, J Wen, L Lei, D Guo - Phytomedicine, 2021 - Elsevier
quinolizidine-type alkaloid isolated from Sophora flavescens … the main bioactive alkaloid
extracted from Sophora flavescens Aiton (… , miRDB and miRanda, we obtained the miR-199a-5p …

Chemical diversity, biological activities and Traditional uses of and important Chinese herb Sophora

P Sun, W Zhao, Q Wang, L Chen, K Sun, Z Zhan… - Phytomedicine, 2022 - Elsevier
… of biological activities associated with Sophora flavescens has … , ‘Kushen’ (Sophora flavescens
Ait.) is all widely used locally. … used as medicine or made into yellow dye. In addition, SF (…

Anti-cancer potential of sophoridine and its derivatives: Recent progress and future perspectives

H ur Rashid, S Rasool, Y Ali, K Khan… - Bioorganic Chemistry, 2020 - Elsevier
… an anticancer agent Sophoridine (C 15 H 24 N 2 O, molecular weight 248.36) is a
quinolizidine-based alkaloid obtainedSophora alopecuroides L., and roots of Sophora

Structural modifications of matrine-type alkaloids

XH Cai, H Guo, B Xie - Mini Reviews in Medicinal Chemistry, 2018 - ingentaconnect.com
… -type alkaloids belong to quinolizidine analogues from Sophora flavescens Ait, Sophora
subprostrata and Sophora … The alkaloid matrine of the root of Sophora flavescens prevents …