Nanoparticle ligand-decoration procedures affect in vivo interactions with immune cells
… targeting efficiency and specificity, it is an important realization in the development of future
ligand-conjugated … affect “nanoparticle in vivo behavior” and interactions with cells, we …
ligand-conjugated … affect “nanoparticle in vivo behavior” and interactions with cells, we …
Peptide ligand-modified nanomedicines for targeting cells at the tumor microenvironment
A David - Advanced drug delivery reviews, 2017 - Elsevier
… aimed at targeting cells in the TME, discusses major obstacles and principles in the
design of ligands for drug targeting and provides an overview of homing peptides in ligand-targeted …
design of ligands for drug targeting and provides an overview of homing peptides in ligand-targeted …
Formulation, characterization, and evaluation of ligand-conjugated biodegradable quercetin nanoparticles for active targeting
… The hydrodynamic particle size was determined by DLS, which … by particles in the
sample. TEM was employed to study the morphology as well as particle size of the ligand-conjugated …
sample. TEM was employed to study the morphology as well as particle size of the ligand-conjugated …
Target gene delivery from targeting ligand conjugated chitosan–PEI copolymer for cancer therapy
JP Nam, JW Nah - Carbohydrate polymers, 2016 - Elsevier
… The pDNA(pEGFP)/HPOCP polyplexes showed high gene transfection efficiency in HCT
119 cell. In addition, siRNA/HPOCP polyplexes formed spherical shape and have particle sizes …
119 cell. In addition, siRNA/HPOCP polyplexes formed spherical shape and have particle sizes …
Designing Functional Bionanoconstructs for Effective In Vivo Targeting
… to controls of nonspecifically engineered particles with adsorbed biomolecular … targeting
ligand conjugated to the nanomaterial surface is successfully recognized and bound by its target …
ligand conjugated to the nanomaterial surface is successfully recognized and bound by its target …
A novel ligand conjugated nanoparticles for oral insulin delivery
… Therefore, in the present study, we attempted to design an intestinal epithelium cell targeting
… (B) Particle size and zeta potential of micelles, T-NPs and FQS-NPs (mean ± SD, n = 3). (C) …
… (B) Particle size and zeta potential of micelles, T-NPs and FQS-NPs (mean ± SD, n = 3). (C) …
Quantification of available ligand density on the surface of targeted liposomal nanomedicines at the single-particle level
C Chen, Y Zhou, C Chen, S Zhu, X Yan - ACS nano, 2022 - ACS Publications
… at the single-particle level for ligand-conjugated liposomes by nFCM. (a) Schematic diagram
of the preparation and ligand quantification processes of ligand-conjugated liposomes. (b) …
of the preparation and ligand quantification processes of ligand-conjugated liposomes. (b) …
… delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target …
… increase the particle diameter compared to non-targeted LCP… vitro anti-tumor activity of
CD siRNA delivered by LCP-FA-scFv NPs The target delivery capability of dual ligand-conjugated …
CD siRNA delivered by LCP-FA-scFv NPs The target delivery capability of dual ligand-conjugated …
Synergetic combinations of dual‐targeting ligands for enhanced in vitro and in vivo tumor targeting
… HA, as a polysaccharide, has various molecular weights that have been demonstrated to
have significant effect on their targeting efficiency. Instead of conjugating HA on the particles …
have significant effect on their targeting efficiency. Instead of conjugating HA on the particles …
Multi-ligand functionalized particle design for cell targeting and drug delivery
JH Yoon, DK Kim, M Na, SY Lee - Biophysical chemistry, 2016 - Elsevier
… ligand-conjugated particle. Our goal was to develop a micro/nano particle-based delivery
system for adhesion to inflamed cells … depend on the particle material and targeted cell types, …
system for adhesion to inflamed cells … depend on the particle material and targeted cell types, …