… Pharmacologic inhibition or shRNA knockdown of ILK prevented periostin-… renal function
and is a key intermediate for periostin activation of signaling pathways involved in cyst growth …

… in OX-161 cells and prevented cyst growth in ex vivo and 3D … retarded cyst development and
mitigated renal function decline. … to evaluate renal function in PKD mice following treatment. …

… in PCs developed significant CD tubular damage and kidney … death shortly after 2 mo of age,
probably due to kidney failure. These … normal kidney structure and renal function after birth. …

… the renal cystogenesis caused by loss of Ift88 is prevented … of autosomal dominant polycystic
kidney disease, indicating that … effects of Itgb1 inactivation on fibrosis in Ift88 KO kidneys, we …

… Inactivation of integrin-β1 prevents the development of polycystic kidney disease after the
loss of polycystin-1. Journal of the American Society of Nephrology : JASN, 26(4), 888–895. …

… Finally, FRET-based probes have been developed, which, after cell transduction, provide a
… to define target molecules for the development of drugs that may help to prevent or cure the …

… FXIIa in patients with diabetes mellitus or chronic kidney disease (… DKD, we treated mice after
16 weeks of persistent hyperglycemia … against integrin β1 almost completely prevented FXII-…

… Herein, we inactivated the E-cadherin gene (Cdh1) … Renal function was assessed by the
measurement of serum … and quantification of integrin α3 and integrin β1 in cultured control and E…

… in PCs developed significant CD tubular damage and kidney … death shortly after 2 mo of age,
probably due to kidney failure. These … normal kidney structure and renal function after birth. …

… of cystic kidney diseases including polycystic kidney disease (… In addition, Integrin β1 both
associates [30] and is cleaved by … Inactivation of ILK in collecting ducts of PKHD1 or pcy mice …