Nuclear accumulation of GAPDH, GluA2 and p53 in post-mortem substantia nigral region of patients with Parkinson's disease

S Sekar, C Taghibiglou - Neuroscience Letters, 2020 - Elsevier
… Similarly, increased caspase 3 level was observed in PD SN … that the increased nuclear
translocation of GluA2, GAPDH and … increase in nuclear GAPDH level may induces the neuronal

Pre-administration of BAX-inhibiting peptides decrease the loss of the nigral dopaminergic neurons in rats

C Ma, Y Pan, Z Yang, Z Meng, R Sun, T Wang, Y Fei… - Life sciences, 2016 - Elsevier
… the enhanced expression of AIF and its nuclear translocation … 9, activated caspase 3 and AIF
nuclear translocation, so we … the immunoreactivity of the activated caspase 9 and caspase 3

Downregulation of Iduna is associated with AIF nuclear translocation in neonatal brain after hypoxia–ischemia

X Yang, J Cheng, Y Gao, J Ding, X Ni - Neuroscience, 2017 - Elsevier
… that AIF nuclear translocation and neuronal cell death are … and nuclear AIF were examined
by immunoblotting, with GAPDH and … For example, Bax inhibition markedly reduced caspase

Neurotoxic effect of ethanolic extract of propolis in the presence of copper ions is mediated through enhanced production of ROS and stimulation of caspase-3/7 …

V Radovanović, J Vlainić, N Hanžić, P Ukić, N Oršolić… - Toxins, 2019 - mdpi.com
… activation is implicated in certain models of neuronal cell … We also examined changes in
Bax expression as Bax is a … in the expression of glyceraldehyde-3-phosphate (GAPDH), a …

Selected gene profiles of stressed NSC‑34 cells and rat spinal cord following peripheral nerve reconstruction and minocycline treatment

G Keilhoff, B Lucas, K Uhde… - Experimental and …, 2016 - spandidos-publications.com
… of the GAPDH reference gene were calculated. Each experiment was repeated in triplicate.
translocation of Bax to the nucleus has previously been described for neonatal neurons of …

p75 neurotrophin receptor and its novel interaction partner, NIX, are involved in neuronal apoptosis after intracerebral hemorrhage

J Shen, X Chen, H Li, Y Wang, K Huo, K Ke - Cell and Tissue Research, 2017 - Springer
… -Bax signaling pathway was activated in apoptotic neurons … and Cl caspase 3 (a’) and for
p-p53, p53 and Bax protein (b’) … to that of the corresponding GAPDH. Each value is the mean ± …

Homocysteine induces glyceraldehyde-3-phosphate dehydrogenase acetylation and apoptosis in the neuroblastoma cell line Neuro2a

M Fang, A Jin, Y Zhao, X Liu - Brazilian Journal of Medical and …, 2016 - SciELO Brasil
… that nuclear translocation and acetylation of GAPDH increased in the presence of 5 mM Hcy
and that higher … , we demonstrated that Hcy induces neuronal cell apoptosis. Interestingly, …

Nesfatin-1 protects dopaminergic neurons against MPP+/MPTP-induced neurotoxicity through the C-Raf–ERK1/2-dependent anti-apoptotic pathway

XL Shen, N Song, XX Du, Y Li, JX Xie, H Jiang - Scientific reports, 2017 - nature.com
… , we recommend you use a more up to date browser (or turn … of caspase-3 and nuclear
fragmentation, as well as caspase-3-… as the percentage of caspase-3-immunoreactive cells out of …

… impairment in focal ischemia through anti-oxidative, anti-inflammatory, and anti-apoptotic effects in primary culture of rat hippocampal neurons and hippocampal CA1 …

CP Wang, YW Shi, M Tang, XC Zhang, Y Gu… - Molecular …, 2017 - Springer
… -binding protein (CREB), Bax, Bcl-2, and caspase-3. Our report provided new … GAPDH was
served as control. … In this present study, nuclear translocation of NF-κB and phosphorylation of …

HIF‑α/PKM2 and PI3K‑AKT pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine‑induced apoptosis in hippocampal neuronal …

F Bao, X Kang, Q Xie, J Wu - Experimental and …, 2019 - spandidos-publications.com
… cell death, accompanied by nuclear fragmentation, cell … cells and expression of caspase 3
and Bax were identified in … while the pro-apoptotic translocation of Bax to the mitochondria and …