Increased occipital gyrification and development of psychotic disorders in individuals with an at-risk mental state: a multicenter study
D Sasabayashi, Y Takayanagi, T Takahashi, S Koike… - Biological …, 2017 - Elsevier
Background Anomalies of brain gyrification have been reported in schizophrenia, possibly
reflecting its neurodevelopmental pathology. However, it remains elusive whether
individuals at risk for psychotic disorders exhibit deviated gyrification patterns, and whether
such findings, if present, are predictive of transition to psychotic disorders. Methods This
multicenter magnetic resonance imaging study investigated brain gyrification and its
relationship to later transition to psychotic disorders in a large sample of at-risk mental state …
reflecting its neurodevelopmental pathology. However, it remains elusive whether
individuals at risk for psychotic disorders exhibit deviated gyrification patterns, and whether
such findings, if present, are predictive of transition to psychotic disorders. Methods This
multicenter magnetic resonance imaging study investigated brain gyrification and its
relationship to later transition to psychotic disorders in a large sample of at-risk mental state …
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