Aquaporin‐4 knockout mice exhibit increased hypnotic susceptibility to ketamine
Y Lv, W Dai, A Ge, Y Fan, G Hu, Y Zeng - Brain and behavior, 2018 - Wiley Online Library
… Ketamine blocks nicotinic acetylcholine ion channels, increases dopaminergic and … or
down-regulation leads to increased seizure duration associated with aberrant neuronal activity (…
down-regulation leads to increased seizure duration associated with aberrant neuronal activity (…
[HTML][HTML] The potential roles of aquaporin 4 in malignant gliomas
YL Lan, X Wang, JC Lou, XC Ma, B Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
… Aquaporin 4 (AQP4) is the major water channel expressed in the central nervous system …
To date, more than 13 water channel proteins (AQP1-13) have been identified in multiple …
To date, more than 13 water channel proteins (AQP1-13) have been identified in multiple …
Aquaporins in neurological disorders
… Mice lacking AQP4 develop less pronounced cerebral … −/− mice were more vulnerable to
epileptic seizures than WT … transient cerebral ischemia in aquaporin-4 knockout mice. J Cereb …
epileptic seizures than WT … transient cerebral ischemia in aquaporin-4 knockout mice. J Cereb …
Chronic inhibition of astrocytic aquaporin-4 induces autistic-like behavior in control rat offspring similar to maternal exposure to valproic acid
… In the present study, we demonstrated that the VPA-exposed offspring had increased
hippocampal water content, and a higher proportion of the fluid volume in this region of the brain as …
hippocampal water content, and a higher proportion of the fluid volume in this region of the brain as …
Aquaporin 4 is involved in chronic pain but not acute pain
G Lu, C Pang, Y Chen, N Wu, J Li - Behavioural brain research, 2020 - Elsevier
… Aquaporin 4 (AQP4), the predominant water channel exists … pain, no differences in the
durations of licking the injected … -/- mice were significantly higher than those of AQP4 +/+ mice 5–…
durations of licking the injected … -/- mice were significantly higher than those of AQP4 +/+ mice 5–…
Astrocyte-Selective Volume Increase in Elevated Extracellular Potassium Conditions Is Mediated by the Na+/K+ ATPase and Occurs Independently of Aquaporin 4
E Walch, TR Murphy, N Cuvelier, M Aldoghmi… - ASN …, 2020 - journals.sagepub.com
… increases. Astrocyte swelling in ^[K + ] o was not dependent on neuronal firing, aquaporin 4,
the inwardly rectifying potassium channel … during seizure (10.5 mM), to a concentration more …
the inwardly rectifying potassium channel … during seizure (10.5 mM), to a concentration more …
Aquaporin-4 deficiency facilitates fear memory extinction in the hippocampus through excessive activation of extrasynaptic GluN2B-containing NMDA receptors
X Wu, JT Zhang, D Li, J Zhou, J Yang, HL Zheng… - …, 2017 - Elsevier
… Aquaporin-4 (AQP-4) is the predominant water channel in the brain and primarily expressed
… The freezing behavior of both WT and KO mice increased remarkably without any significant …
… The freezing behavior of both WT and KO mice increased remarkably without any significant …
Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin‐4 channelopathies: a decade later
SJ Pittock, CF Lucchinetti - Annals of the new York Academy of …, 2016 - Wiley Online Library
… antibody that targets the astrocytic water channel aquaporin-4), as the … We suspect that the
duration of follow-up may not be long … Mice lacking AQP4 have better outcomes in models of …
duration of follow-up may not be long … Mice lacking AQP4 have better outcomes in models of …
Cortical astrogliosis and increased perivascular aquaporin-4 in idiopathic intracranial hypertension
PK Eide, VA Eidsvaag, EA Nagelhus, HA Hansson - Brain research, 2016 - Elsevier
… As astrocytic aquaporin-4 (AQP4) water channels play key … In D (patient 24 – epilepsy)
higher magnification disclosed … significant positive correlation between duration of disease and …
higher magnification disclosed … significant positive correlation between duration of disease and …
The role of aquaporin‐4 and transient receptor potential vaniloid isoform 4 channels in the development of cytotoxic edema and associated extracellular diffusion …
M Chmelova, P Sucha, M Bochin… - European Journal of …, 2019 - Wiley Online Library
… Overall, our results indicate that the AQP4 and TRPV4 channels may play a crucial role in …
and enhanced cell swelling. However, detailed interplay between AQP4 and TRPV4 channels …
and enhanced cell swelling. However, detailed interplay between AQP4 and TRPV4 channels …