… many aspects of the biochemical, cell and molecular bases of … of genetic factors is stronger
in certain types of alcoholism and … that individual differences in endorphin sensitivity underlay …

… In the biological sphere we must conceptualize both genetic and experiential … One such
formulation has achieved 100% sensitivity for excessive drinking and alcoholism, without any …

… constitutional, environmental and genetic factors, although the … The determinants of disease
susceptibility are complex and … adopted in early childhood with those of their biological and …

… susceptible individuals with specific risk factors. Through CYP 2E1-dependent ROS, more
evidence is emerging that alcohol … a rapid diffusion of ethanol through biological membranes, …

… alcohol, women are more susceptible to ALD than men. Studies of ethnic differences 52 and
twin studies have indicated that genetic factors … with no evidence for a biochemical effect on …

… Recent efforts in the search for AUD susceptibility genes will be … , and biological relevance
is often unknown. … Because of the epidemiological evidence for genetic factors in AUD, the …

… [47, 48] Several other genetic variants have been suggested to contribute to individual
susceptibility to ALD. These include variants of alcohol-metabolizing enzymes, genes involved in …

… of alcohol metabolism [24] where several biochemical agents … genetic factors. Research
findings aggregately indicate that … determinants of individual differences in ethanol sensitivity [64]…

… of sensitivity to PF in rats as a stable and enduring trait, with the examination of the
impact of this trait on individual susceptibility to the acquisition and maintenance of alcohol-seeking …

… addiction, to help understand the biological mechanisms involved and which may be useful
… Smoking is influenced by genetic factors including variations in CYP2A6 and CYP2B6, …