[HTML][HTML] Role of regulatory T cell in the pathogenesis of inflammatory bowel disease

…, R Arakaki, M Saito, T Tsunematsu… - World journal of …, 2016 - ncbi.nlm.nih.gov
… immune system activation in response to bacterial antigens and pathologic cytokine production
by intestinal T cells is induced through various transcription factors or signal molecules, …

Peripheral and intestinal T-regulatory cells are upregulated in children with inflammatory bowel disease at onset of disease

K Sznurkowska, A Żawrocki, J Sznurkowski… - Immunological …, 2016 - Taylor & Francis
regulatory T cells at the time of diagnosis, as such providing better insight into the immunological
background of the disease. … to contain induced Tregs that differentiate in the gut upon …

[HTML][HTML] Disrupted regulatory T cell homeostasis in inflammatory bowel diseases

C Pedros, F Duguet, A Saoudi… - World journal of …, 2016 - ncbi.nlm.nih.gov
… Tfh differentiation factor BCL6 by Tregs induces CXCR5 expression, promoting Treg migration
into the germinal center (GC), where they become T follicular regulatory T cells (Tfr). The …

Development and maintenance of intestinal regulatory T cells

T Tanoue, K Atarashi, K Honda - Nature Reviews Immunology, 2016 - nature.com
… and tissue damage in patients with inflammatory bowel diseases (IBDs) 1,… regulatory T (tT
reg ) cell differentiation programme is initiated by strong T cell receptor (TCR) signals induced

Intestinal regulatory T cells as specialized tissue-restricted immune cells in intestinal immune homeostasis and disease

J Jacobse, J Li, EHHM Rings, JN Samsom… - Frontiers in …, 2021 - frontiersin.org
inflammatory bowel disease. Here, the induction, maintenance, trafficking, and function of
intestinal … -derived TGFβ induction converts circulating naïve T cells into pTreg cells, which is …

The function and role of the Th17/Treg cell balance in inflammatory bowel disease

J Yan, M Luo, Z Chen, B He - Journal of immunology research, 2020 - Wiley Online Library
cells and thereby controlling inflammation [9]. According to their origin, natural regulatory T
(nTreg) cells … -/- cells induced immature T lymphocytes to preferentially differentiate into Treg …

Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease

C Hao, W Wang, B Zhan, Z Wang, J Huang… - … and Developmental …, 2021 - frontiersin.org
… To determine if rTsPmy plays a role in stimulating Tregs to maintain their suppressive status
in inflammatory colon, we measured the effector regulatory T cells (eTregs) which express …

Tryptophan metabolism, regulatory T cells, and inflammatory bowel disease: a mini review

X Ding, P Bin, W Wu, Y Chang… - Mediators of inflammation, 2020 - Wiley Online Library
… lymphoid cells play important roles in the development of IBD… function of certain T lymphocytes
[eg, regulatory T cells (Tregs)] … Kyn induced the transformation of naive CD4 + T cells into …

Analysis of murine and human Treg subsets in inflammatory bowel disease

X Sun, S He, C Lv, X Sun, J Wang… - Molecular …, 2017 - spandidos-publications.com
… of natural regulatory T-cell subsets in DSS-induced colitis The best-characterized regulatory
T cell population is the natural regulatory T cell … whether the natural regulatory T cell subset …

Induced regulatory T cells: their development, stability, and applications

M Kanamori, H Nakatsukasa, M Okada, Q Lu… - Trends in …, 2016 - cell.com
… iTregs could be a crucial source of regulatory T cells for … In tTreg cells, Foxp3 has been
shown to be induced by strong T cellcells (APCs) with relatively high avidity. Therefore, tTreg …