In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36
KMF Mustaffa, J Storm, M Whittaker, T Szestak… - Malaria journal, 2017 - Springer
… is caused by an interaction between the parasite protein … on pRBC associated with placenta
malaria and subsequent … than the adhesion itself or the induction of cross-reactive immunity …
malaria and subsequent … than the adhesion itself or the induction of cross-reactive immunity …
Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria
…, A Salanti, M Resende, R Dzikowski, P Damm… - Malaria journal, 2016 - Springer
… model of parasite adhesion in intact placental tissue. … endemic regions develop protective
antibodies during childhood. … of a vaccine to induce antibodies that inhibit the binding of …
antibodies during childhood. … of a vaccine to induce antibodies that inhibit the binding of …
Reduced risk of placental parasitemia associated with complement fixation on Plasmodium falciparum by antibodies among pregnant women
… Parasite accumulation in the placenta is a key feature of MiP following infection with Plasmodium
falciparum [2… the complement fixing activity of antibodies induced by vaccines based on …
falciparum [2… the complement fixing activity of antibodies induced by vaccines based on …
Malaria Parasite Plasmodium falciparum Proteins on the Surface of Infected Erythrocytes as Targets for Novel Drug Discovery
AV Oleinikov - Biochemistry (Moscow), 2022 - Springer
… antibodies preventing IE cytoadhesion to the placental syncytiotrophoblast in multigravid
women is associated with protection against … PM, and is characterized by induction of adhesion …
women is associated with protection against … PM, and is characterized by induction of adhesion …
Functional antibodies against placental malaria parasites are variant dependent and differ by geographic region
… are at high risk of Plasmodium falciparum infection resulting in placental malaria (PM), which
… A vaccine that can induce antibodies with broadly neutralizing activity is key to ensuring its …
… A vaccine that can induce antibodies with broadly neutralizing activity is key to ensuring its …
VAR2CSA Domain-Specific Analysis of Naturally Acquired Functional Antibodies to Plasmodium falciparum Placental Malaria
JYA Doritchamou, R Herrera, JA Aebig… - The Journal of …, 2016 - academic.oup.com
… the parasites in the placenta [6]. Placental parasites predominantly express a member of
P. … Whether antibody induced by animal immunization with recombinant protein displays a …
P. … Whether antibody induced by animal immunization with recombinant protein displays a …
P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission
…, C Clapham, F Baiwog, M Pimanpanarak, P Siba… - PloS one, 2017 - journals.plos.org
… falciparum infection may also impact maternofetal antibody … through the induction of
pathological changes in the placenta including … in the placenta (pathology class 1–3) to no …
pathological changes in the placenta including … in the placenta (pathology class 1–3) to no …
Interaction between endothelial protein C receptor and intercellular adhesion molecule 1 to mediate binding of Plasmodium falciparum-infected erythrocytes to …
… We show that two parasite lines expressing domain cassette 13 (DC13) of the P. … Percent
inhibition is based on parasite binding levels in the absence of antibody treatment. The bar …
inhibition is based on parasite binding levels in the absence of antibody treatment. The bar …
VAR2CSA-Mediated Host Defense Evasion of Plasmodium falciparum Infected Erythrocytes in Placental Malaria
A Tomlinson, JP Semblat, B Gamain… - Frontiers in …, 2021 - frontiersin.org
… PAMVAC trials nevertheless revealed that vaccine-induced antibodies had a limited capability
to cross-react with VAR2CSA originating from heterologous parasite strains (133, 134), …
to cross-react with VAR2CSA originating from heterologous parasite strains (133, 134), …
[HTML][HTML] Comparison of functional assays used in the clinical development of a placental malaria vaccine
C Pehrson, KK Heno, Y Adams, M Resende… - Vaccine, 2017 - Elsevier
… induced antibodies that inhibited IE adhesion in placental … Infection with Plasmodium
falciparum in pregnancy is … CSA is abundant in the placenta, and parasites bind both to the …
falciparum in pregnancy is … CSA is abundant in the placenta, and parasites bind both to the …