Vaccination with MIP or Pgp3 induces cross-serovar protection against chlamydial genital tract infection in mice
X Luan, B Peng, Z Li, L Tang, C Chen, L Chen, H Wu… - Immunobiology, 2019 - Elsevier
… This study aimed to evaluate the immunogenicity of MIP and Pgp3 from C. trachomatis … MIP
and Pgp3 can induce cross-serovar protective against chlamydial genital tract infection, and …
and Pgp3 can induce cross-serovar protective against chlamydial genital tract infection, and …
Chlamydia trachomatis Cross-Serovar Protection during Experimental Lung Reinfection in Mice
C Lanfermann, M Kohn, R Laudeley, C Rheinheimer… - Vaccines, 2021 - mdpi.com
… A better understanding of induced cross-serovar protection is … Potential sequelae of an
untreated chlamydial genital infection … Hence, in this study, we aimed to clarify this point as a proof …
untreated chlamydial genital infection … Hence, in this study, we aimed to clarify this point as a proof …
Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go?
LM de la Maza, TL Darville, S Pal - Expert review of vaccines, 2021 - Taylor & Francis
… induce partial protection against infection in females, but a vaccine targeting males may be
required to protect females against … broad cross-serovar protection against genital and ocular …
required to protect females against … broad cross-serovar protection against genital and ocular …
A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars
AW Olsen, I Rosenkrands, MJ Holland, P Andersen… - npj Vaccines, 2021 - nature.com
… and designed to target ocular and genital serovars from C complex serovars. … focused on
developing a vaccine construct with the ability to induce broadly neutralizing antibodies against …
developing a vaccine construct with the ability to induce broadly neutralizing antibodies against …
Cross-reactive effects of vaccines: Heterologous immunity between tetanus and chlamydia
M Stojanovic, I Lukic, E Marinkovic, A Kovacevic… - Vaccines, 2020 - mdpi.com
… Our data provide insights that tetanus immunization generates antibodies which induce
heterologous chlamydial immunity and promote protection beyond the intended target pathogen. …
heterologous chlamydial immunity and promote protection beyond the intended target pathogen. …
Update on Chlamydia trachomatis vaccinology
LM de la Maza, G Zhong… - Clinical and Vaccine …, 2017 - Am Soc Microbiol
… to protect against Chlamydia trachomatis-induced trachoma … of isolates that will allow testing
for cross-serovar protection. … immune responses and are often targeted to a single type of …
for cross-serovar protection. … immune responses and are often targeted to a single type of …
Efficacy of Pgp3 vaccination for Chlamydia urogenital tract infection depends on its native conformation
B Peng, S Zhong, Y Hua, Q Luo, W Dong… - Frontiers in …, 2022 - frontiersin.org
… urogenital epithelial cells, and serovars L1 to L3 mainly target the lymphatic tissue (1). All C.
… adjuvant induced cross-serovar protection against C. muridarum genital tract infections (17). …
… adjuvant induced cross-serovar protection against C. muridarum genital tract infections (17). …
Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non …
E Lorenzen, V Contreras, AW Olsen… - Frontiers in …, 2022 - frontiersin.org
… Genital Chlamydia trachomatis infections annually cause an … The strategies aimed to induce
antibodies, CD4 T cells and/… protective epitopes and induce cross-serovar protection (11). …
antibodies, CD4 T cells and/… protective epitopes and induce cross-serovar protection (11). …
Multistage vaccines containing outer membrane, type III secretion system and inclusion membrane proteins protects against a Chlamydia genital tract infection and …
… protection against vaginal shedding and upper genital tract pathology than vaccines targeting
… 3) induced the greatest protection against vaginal shedding. To determine if administering …
… 3) induced the greatest protection against vaginal shedding. To determine if administering …
A Multi-Component Prime-Boost Vaccination Regimen with a Consensus MOMP Antigen Enhances Chlamydia trachomatis Clearance
… human studies to be important in chlamydial protection and (ii) … clinical cases of genital
chlamydial infections in the US alone … immunogen that would induce cross-serovar Chlamydial T-…
chlamydial infections in the US alone … immunogen that would induce cross-serovar Chlamydial T-…