[HTML][HTML] Novel Tissue Level Effects of the Staphylococcus aureus Enterotoxin Gene Cluster Are Essential for Infective Endocarditis

CS Stach, BG Vu, JA Merriman, A Herrera, MP Cahill… - PloS one, 2016 - journals.plos.org
… Likewise, rabbits are sensitive to the toxic effects of SAgs, whereas mice are highly resistant
… , both severe effects studied in this manuscript. We have experimentally determined over …

S. aureus endocarditis: clinical aspects and experimental approaches

V Hoerr, M Franz, MW Pletz, M Diab, S Niemann… - International Journal of …, 2018 - Elsevier
… The aetiologic change has impact on the pathophysiology of IE, … rabbit endocarditis model,
it could further been shown that the probability to induce endocarditis is higher with CC30 S

Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves

L Liesenborghs, S Meyers, M Lox, M Criel… - European heart …, 2019 - academic.oup.com
… In a first experiment, we mimicked three different clinically … had no effect on bacterial binding
(P = 0.10; Figure 5C). … rabbit, which then acts as a seeding ground for intravenously injected …

Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis

…, G Carlucci, KP Riddell, S Barney… - Science translational …, 2020 - science.org
… anatomy, experiments in pigs with endocarditis could address … with horseradish
peroxidase–labeled rabbit anti-mouse IgG … impact of eliminating prothrombin activation by …

[PDF][PDF] … OF ThE IMMUNOGENICITy OF rEVErSE-VaCCINOLOGy DErIVED STAPHYLOCOCCUS AUREUS PrOTEINS ON EXPErIMENTaL ENDOCarDITIS MODEL

M Oprea, B Cordoş, M Strău&B… - Romanian Archives of …, 2019 - researchgate.net
experiment and also for the infection of vaccinated rabbits. … Rabbit sera tested for specific
antibodies in ELISA assays … colonization: Modulation of host immune response and impact

[HTML][HTML] Isolating crucial steps in induction of infective endocarditis with preclinical modeling of host pathogen interaction

…, U Hansen, H Van de Vyver, S Niemann… - Frontiers in …, 2020 - frontiersin.org
… models of Staphylococcus aureus infective endocarditis (IE), … we systematically investigated
the influence of the degree of … from the slice and secondary antibody goat-anti-rabbit (Biotin) (…

Host-pathogen interactions of clinical S. aureus isolates to induce infective endocarditis

C Schwarz, Y Töre, V Hoesker, S Ameling, K Grün… - Virulence, 2021 - Taylor & Francis
… In preparation for the infection experiments bacteria from overnight culture in Tryptic Soy Broth
(TSB) (shaking conditions, 37 … Another potential factor might be the destructive effect of S. …

Neutrophils Protect Against Staphylococcus aureus Endocarditis Progression Independent of Extracellular Trap Release

S Meyers, M Lox, S Kraisin… - … and Vascular Biology, 2023 - Am Heart Assoc
… To study the effect of bacterial factors on progression of IE, … with a rabbit anti-H3Cit and a
gold-conjugated anti-rabbit antibody. … .com) of endocarditis experiments performed in neutrophil-…

Neutrophil extracellular traps enhance Staphylococcus aureus vegetation formation through interaction with platelets in infective endocarditis

CC Hsu, RB Hsu, RL Ohniwa, JW Chen… - Thrombosis and …, 2019 - thieme-connect.com
… Using an experimental endocarditis rat model, here we … by Western blot using rabbit antibodies
against citrullinated histone … The effect of DNase I in other Staphylococcus aureus strains-…

[HTML][HTML] Performance of a Four-Antigen Staphylococcus aureus Vaccine in Preclinical Models of Invasive S. aureus Disease

IL Scully, Y Timofeyeva, A Illenberger, P Lu… - Microorganisms, 2021 - mdpi.com
… The reaction mixtures were then mixed with baby rabbit … illustrating an impact of SA4Ag in
this difficult local infection model. … aureus-induced foreign body infections and endocarditis are …