Shear-Resistant Binding to von Willebrand Factor Allows Staphylococcus lugdunensis to Adhere to the Cardiac Valves and Initiate Endocarditis

…, M Lox, WE Peetermans, S Heilbronner… - The Journal of …, 2016 - academic.oup.com
… Moreover, besides activating platelets, Staphylococcus aureus also … Moreover, platelets did
not influence bacterial adhesion … experiments with VWF deletion mutants, we believe that, for …

[HTML][HTML] Staphylococcus aureus Host Tropism and Its Implications for Murine Infection Models

…, D Raafat, S Holtfreter - International journal of …, 2020 - mdpi.com
aureus strains massively influences the experimental … major experimental findings by testing
a variety of relevant S. … activity in mice, such as the use of rabbits for studying PVL, HlgCB, or …

[HTML][HTML] Monoclonal Antibody Targeting Staphylococcus aureus Surface Protein A (SasA) Protect Against Staphylococcus aureus Sepsis and Peritonitis in Mice

Y Yang, M Qian, S Yi, S Liu, B Li, R Yu, Q Guo… - PLoS …, 2016 - journals.plos.org
… (MRSA) imposes an increasing impact on public health. Due to … aureus to platelets and
contributes to infective endocarditis [20]… Rabbit serum (1%) was added to reduce the non-specific …

[HTML][HTML] Molecular targets for antibody-based anti-biofilm therapy in infective endocarditis

J Han, A Poma - Polymers, 2022 - mdpi.com
… -ClfA mAb, contributed to the prevention of IE in a rabbit model [44]. However, tefibazumab
has … This study shows MEDI4893 could exert its neutralising effect through a dual mechanism, …

Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing

L Thomer, C Emolo, V Thammavongsa… - Journal of Experimental …, 2016 - rupress.org
aureus agglutination of EDTA-rabbit plasma (Fig. 3, C and D). Purified … antibody against the
R domain can target staphylococci for OPK. Successful vaccines generally rely on antibodies

Ability of Bicarbonate Supplementation To Sensitize Selected Methicillin-Resistant Staphylococcus aureus Strains to β-Lactam Antibiotics in an Ex Vivo Simulated …

WE Rose, AM Bienvenida, YQ Xiong… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
… The more active effect of CFZ in our ex vivo SEV model, as well as in the rabbit endocarditis
… Louis, MO) and prepared fresh prior to each experiment according to the manufacturer’s

[HTML][HTML] Rapid and Broad Immune Efficacy of a Recombinant Five-Antigen Vaccine against Staphylococcus aureus Infection in Animal Models

…, H Jing, C Cai, L Xu, X Yang, X Xia, N Zeng, S Fan… - Vaccines, 2020 - mdpi.com
… All animal experiments in this study were approved by the … polyclonal antibodies (rFSAV-pcAb)
were generated in rabbits … antigens to remove harmful toxic effects and maintain good …

Clearance of Staphylococcus aureus from In Vivo Models of Chronic Infection by Immunization Requires Both Planktonic and Biofilm Antigens

…, DL Allison, KJ Brao, DP Marinos, S Sanjari… - Infection and …, 2019 - Am Soc Microbiol
… tissue infections, pneumonia, endocarditis, and osteomyelitis and … in the rabbit model of
osteomyelitis. New Zealand White … aureus will have a large impact on the global human health …

Antibody-mediated protection against Staphylococcus aureus dermonecrosis and sepsis by a whole cell vaccine

F Zhang, M Jun, O Ledue, M Herd, R Malley, YJ Lu - Vaccine, 2017 - Elsevier
effect against skin abscesses, suggesting that antibodies alone may … to protect animals in
a rabbit endocarditis model. Whole cell … We chose rabbit serum as a source of antibody in the …

Antibodies to Staphylococcus aureus capsular polysaccharides 5 and 8 perform similarly in vitro but are functionally distinct in vivo

B Liu, S Park, CD Thompson, X Li, JC Lee - Virulence, 2017 - Taylor & Francis
… Human mAbs that neutralize the cytotoxic effects S. … then incubated with polyclonal rabbit
antibodies specific for CP5 or … with experimental endocarditis due to Staphylococcus aureus. J …