A novel bivalent fusion vaccine induces broad immunoprotection against Staphylococcus aureus infection in different murine models

L Yang, H Zhou, P Cheng, Y Yang, Y Tong, Q Zuo… - Clinical …, 2018 - Elsevier
… Further we demonstrated the protective effect of antibodies … bacteraemia, infective endocarditis
or continuous ambulatory … on mice to generate rabbit polyclonal antibodies. Serum was …

Identification of a Human Anti-Alpha-Toxin Monoclonal Antibody Against Staphylococcus aureus Infection

F Liu, Z Guan, Y Liu, J Li, C Liu, Y Gao, Y Ma… - Frontiers in …, 2021 - frontiersin.org
antibody YG1 blocked the Hla-mediated lysis of rabbit red … Based on these results, we further
investigated the effects of YG1 … In this experiment, YG1 or the IgG1 isotype control YG2, was …

Recent advances in Staphylococcus aureus infection: focus on vaccine development

S Ansari, RK Jha, SK Mishra, BR Tiwari… - Infection and drug …, 2019 - Taylor & Francis
… approach can have a positive impact on treatment of staphylococcal diseases remain to be
… of anti-staphylococcal antibodies by injecting 200 μL of rAdsA immunized rabbit antisera into …

Panton–Valentine leucocidin colocalized with retinal neurons cells and incited early retinal inflammation through rabbit endophthalmitis and retinal explant models

X Liu - 2018 - theses.hal.science
Staphylococcus aureus was first discovered in 1871. It was … This study of its effects on
organic tissue and especially retina … All those PVL inhibitors are still in an experimental stage. …

Investigational drugs to treat methicillin-resistant Staphylococcus aureus

C Vuong, AJ Yeh, GYC Cheung… - Expert opinion on …, 2016 - Taylor & Francis
… ABSSSI has been completed and some adverse effects were … aureus challenge, rabbits
were immunized with one or a … aureus challenge in an infective endocarditis model. Finally, …

Staphylococcus aureus TSST-1 and β-toxin contribute to infective endocarditis via multiple mechanisms

A Herrera - 2016 - search.proquest.com
… The SAgs may be the cause of many of the systemic effects seen in these patients. In a
rabbit … into the rabbits intravenously and the experiment allowed to progress for up to 4 days. …

[HTML][HTML] Staphylococcus aureus, master manipulator of the human hemostatic system

L Liesenborghs, P Verhamme, T Vanassche - Journal of Thrombosis and …, 2018 - Elsevier
… ) and fibrin (yellow) in an experimental endocarditis lesion. [Color figure can be … endocarditis
in rabbit or rat models 92., 93.. There are no studies on the effect of platelet depletion in S. …

Staphylococcal protein A contributes to persistent colonization of mice with Staphylococcus aureus

Y Sun, C Emolo, S Holtfreter, S Wiles… - Journal of …, 2018 - Am Soc Microbiol
… , pneumonia, bacteremia, and endocarditis (1). Between 20 and … Here, we demonstrate that
the vaccine effect of SpA KKAA … Two different rabbit anti-vWbp polyclonal antibodies (1:1,000 …

Monoclonal antibodies targeting surface-exposed and secreted proteins from staphylococci

P Speziale, G Pietrocola - Vaccines, 2021 - mdpi.com
… , bacteremia, sepsis and endocarditis. The widespread and … inhibitory protein of Staphylococcus
aureus). CHIPS binds the … have beneficial effects against staphylococcal infections. For …

A comparative study on the effects of vancomycin, enrofloxacin, and trimethoprim/sulfamethoxazole on methicillin-resistant Staphylococcus aureus osteomyelitis in an …

A Taghipour, SM Rafiei, MN Masouleh… - Comparative Clinical …, 2020 - Springer
… Zealand adult white rabbits were experimentally infected by … endocarditis caused by
methicillin-resistant Staphylococcus … was observed for Staphylococcus aureus antibodies isolated …