Increases in ambient air pollutants during pregnancy are linked to increases in methylation of IL4, IL10, and IFNγ

J Aguilera, X Han, S Cao, J Balmes, F Lurmann… - Clinical …, 2022 - Springer
… mid-term AAP exposures to fine particulate matter (PM 2.5 ), … elevated AAP levels, we found
levels of AAPs to be associated with alterations in both pro and anti-inflammatory cytokines

Pregnancy protects against the pro-inflammatory respiratory responses induced by particulate matter exposure

S Thaver, EJ Bennett, L Foa, SM Richards, AB Lyons… - Chemosphere, 2019 - Elsevier
… The concentrations of IL-4 and IL-6 in the serum were … shown that pregnancy increased
serum and BAL IL-4 levels. … the lung inflammatory response induced by inhalation of PM. …

… intervention modulates hypothalamic-pituitary-thyroid/gonadal axes by attenuating inflammatory responses in adult rats after fine particulate matter (PM2. 5) exposure

C Liu, J Yang, X Du, X Geng - Environmental Science and Pollution …, 2022 - Springer
… However, IL-6 and IL-1β levels in female rats and only TNF α level in both male and female
increased the IL-4 and IL-10 mRNA levels only in male rats after PM2.5 inhalation. These …

Influence of residential exposure to traffic-related fine particulate matter on umbilical cord blood cytokine levels: a birth cohort study

A García-Serna, E Martin-Orozco… - Environmental …, 2019 - journals.lww.com
… , Nickel and Lead through the inhalation, ingestion and dermal … Results: Median PM2.5
concentration during pregnancy was … with: increased response of TNF-alpha, IL-5, IL-6, IL1-beta …

[PDF][PDF] The early life effects of maternal exposure to particulate matter

S Thaver - 2021 - figshare.utas.edu.au
pregnant mice had elevated levels of IL-4 and suppressed … Inhalation of particulate matter
(PM), the solid and liquid … of Th2 cytokines such as IL-4 and IL-10 in the decidua during

Air pollution during pregnancy and cord blood immune system biomarkers

J Ashley-Martin, E Lavigne, TE Arbuckle… - … of occupational and …, 2016 - journals.lww.com
… to pollutants, including diesel and particulate matter, promotes susceptibility to asthma and
… may be more likely to promote Th2 cytokine response than exposure earlier in pregnancy. …

Exposure of trophoblast cells to fine particulate matter air pollution leads to growth inhibition, inflammation and ER stress

M Familari, Å Nääv, L Erlandsson, RU de Iongh… - PloS one, 2019 - journals.plos.org
… between levels of PM pollution and pregnancy complications … in rodents that inhaled PM
during pregnancy not only reach … In particular, PM cause increased levels of cytokine release …

Inflammatory cytokines and DNA methylation in healthy young adults exposure to fine particulate matter: A randomized, double-blind crossover trial of air filtration

Y Sun, J Huang, Y Zhao, L Xue, H Li, Q Liu… - Journal of hazardous …, 2020 - Elsevier
Inhaled PM 2.5 triggers the release of cytokines in the blue … with the elevated levels in
IFN-α2, IL-1RA, and IL-4. Several … to particulate matter increased the levels of IL-1RA and IL-4 (…

Air pollution and children's health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter

NM Johnson, AR Hoffmann, JC Behlen, C Lau… - … health and preventive …, 2021 - Springer
… Laboratory-based inhalation toxicology studies using in vivo … associated with increase in
stillbirth risk through pregnancy, first … how PM 2.5 exposure during pregnancy leads to metabolic …

In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression

KA Rychlik, JR Secrest, C Lau… - Proceedings of the …, 2019 - National Acad Sciences
… Sensitization followed by inhalation challenge with the egg … inflammation driven by increased
Th2-cytokine production. … of cytokines associated with a Th1 (IFNγ), Th2 (IL-4, IL-5, Il-13)…